日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein

呼吸道合胞病毒特异性中和单克隆抗体帕利珠单抗逃避中和作用的机制是融合蛋白结合率的变化

John T Bates, Christopher J Keefer, James C Slaughter, Daniel W Kulp, William R Schief, James E Crowe Jr

Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency

呼吸道合胞病毒特异性人单克隆抗体 Fab19 体细胞突变的逆转揭示了结合率与中和效力之间的直接关系

John T Bates, Christopher J Keefer, Thomas J Utley, Bruno E Correia, William R Schief, James E Crowe Jr

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

源自 1918 年流感大流行幸存者 B 细胞的中和抗体

Xiaocong Yu, Tshidi Tsibane, Patricia A McGraw, Frances S House, Christopher J Keefer, Mark D Hicar, Terrence M Tumpey, Claudia Pappas, Lucy A Perrone, Osvaldo Martinez, James Stevens, Ian A Wilson, Patricia V Aguilar, Eric L Altschuler, Christopher F Basler, James E Crowe Jr

A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo

一种重组人单克隆抗体,用于抗人亚肺病毒融合蛋白,可在体外中和病毒,并在体内具有治疗效果

John V Williams, Zhifeng Chen, Gabriella Cseke, David W Wright, Christopher J Keefer, Sharon J Tollefson, Ann Hessell, Amy Podsiad, Bryan E Shepherd, Pietro Paolo Sanna, Dennis R Burton, James E Crowe Jr, R Anthony Williamson