日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence

脱氧核糖核苷酸池的消耗是致癌基因诱导衰老细胞中 DNA 损伤的内源性原因

Sudha Mannava, Kalyana C Moparthy, Linda J Wheeler, Venkatesh Natarajan, Shoshanna N Zucker, Emily E Fink, Michael Im, Sheryl Flanagan, William C Burhans, Nathalie C Zeitouni, Donna S Shewach, Christopher K Mathews, Mikhail A Nikiforov

Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion

核苷酸还原酶和胸苷酸合成酶或外源脱氧核糖核苷可减少 C-MYC 耗竭引起的 DNA 损伤和衰老

Sudha Mannava, Kalyana C Moparthy, Linda J Wheeler, Katerina I Leonova, Joseph A Wawrzyniak, Anna Bianchi-Smiraglia, Albert E Berman, Sheryl Flanagan, Donna S Shewach, Nathalie C Zeitouni, Andrei V Gudkov, Christopher K Mathews, Mikhail A Nikiforov

Initiation of genome instability and preneoplastic processes through loss of Fhit expression

通过Fhit表达的丧失引发基因组不稳定性和肿瘤前过程

Joshua C Saldivar, Satoshi Miuma, Jessica Bene, Seyed Ali Hosseini, Hidetaka Shibata, Jin Sun, Linda J Wheeler, Christopher K Mathews, Kay Huebner

E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin

E2F4 和核苷酸还原酶介导用叶绿素处理的结肠癌细胞的 S 期停滞

Korakod Chimploy, G Dario Díaz, Qingjie Li, Orianna Carter, Wan-Mohaiza Dashwood, Christopher K Mathews, David E Williams, George S Bailey, Roderick H Dashwood

Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells

核苷酸代谢在 C-MYC 依赖性黑色素瘤细胞增殖中的直接作用

Sudha Mannava, Vladimir Grachtchouk, Linda J Wheeler, Michael Im, Dazhong Zhuang, Elena G Slavina, Christopher K Mathews, Donna S Shewach, Mikhail A Nikiforov

p53 mediates senescence-like arrest induced by chronic replicational stress

p53 介导慢性复制应激引起的衰老样停滞

Andriy Marusyk, Linda J Wheeler, Christopher K Mathews, James DeGregori

Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia

Slc25a19 敲除会导致线粒体硫胺素焦磷酸耗竭、胚胎致死、中枢神经系统畸形和贫血

Marjorie J Lindhurst, Giuseppe Fiermonte, Shiwei Song, Eduard Struys, Francesco De Leonardis, Pamela L Schwartzberg, Amy Chen, Alessandra Castegna, Nanda Verhoeven, Christopher K Mathews, Ferdinando Palmieri, Leslie G Biesecker