日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Long-Term CD4+ T-Cell and Immunoglobulin G Immune Responses in Oncology Workers following COVID-19 Vaccination: An Interim Analysis of a Prospective Cohort Study

肿瘤科工作人员接种 COVID-19 疫苗后的长期 CD4+ T 细胞和免疫球蛋白 G 免疫反应:一项前瞻性队列研究的中期分析

Corey Gallen, Christopher W Dukes, Amy Aldrich, Lauren Macaisa, Qianxing Mo, Christopher L Cubitt, Shari Pilon-Thomas, Anna R Giuliano, Brian J Czerniecki, Ricardo L B Costa

Melphalan and Exportin 1 Inhibitors Exert Synergistic Antitumor Effects in Preclinical Models of Human Multiple Myeloma

美法仑和 Exportin 1 抑制剂在人类多发性骨髓瘤临床前模型中发挥协同抗肿瘤作用

Joel G Turner #, Yan Cui #, Alexis A Bauer, Jana L Dawson, Juan A Gomez, Jongphil Kim, Christopher L Cubitt, Taiga Nishihori, William S Dalton, Daniel M Sullivan

Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia

Selinexor 与柔红霉素和阿糖胞苷联合治疗未经治疗的高风险急性髓系白血病的 I 期临床试验

Kendra Sweet, Rami Komrokji, Eric Padron, Christopher L Cubitt, Joel G Turner, Junmin Zhou, Alan F List, David A Sallman, Jana L Dawson, Daniel M Sullivan, Julio Chavez, Bijal D Shah, Jeffrey E Lancet

Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines

在尤文氏肉瘤细胞系中,单独或联合使用小分子抑制赖氨酸特异性去甲基化酶 1 (LSD1) 和组蛋白去乙酰化酶 (HDAC)

Darcy Welch, Elliot Kahen, Brooke Fridley, Andrew S Brohl, Christopher L Cubitt, Damon R Reed

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors

神经纤维蛋白水平指导 RAS 通路信号传导并介导恶性外周神经鞘肿瘤对靶向药物的敏感性

Elliot John Kahen, Andrew Brohl, Diana Yu, Darcy Welch, Christopher L Cubitt, Jae K Lee, Yunyun Chen, Sean J Yoder, Jamie K Teer, Yonghong O Zhang, Margaret R Wallace, Damon R Reed

Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma

确定具有协同作用且临床可行、针对骨肉瘤的联合疗法

Diana Yu, Elliot Kahen, Christopher L Cubitt, Jeremy McGuire, Jenny Kreahling, Jae Lee, Soner Altiok, Conor C Lynch, Daniel M Sullivan, Damon R Reed

Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival

抑制内质网应激相关 IRE-1/XBP-1 通路可降低白血病细胞存活率

Chih-Hang Anthony Tang, Sujeewa Ranatunga, Crystina L Kriss, Christopher L Cubitt, Jianguo Tao, Javier A Pinilla-Ibarz, Juan R Del Valle, Chih-Chi Andrew Hu

Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases

高效选择性二氨基噻唑细胞周期依赖性激酶抑制剂的开发

Ernst Schonbrunn, Stephane Betzi, Riazul Alam, Mathew P Martin, Andreas Becker, Huijong Han, Rawle Francis, Ramappa Chakrasali, Sudhakar Jakkaraj, Aslamuzzaman Kazi, Said M Sebti, Christopher L Cubitt, Anthony W Gebhard, Lori A Hazlehurst, Joseph S Tash, Gunda I Georg

MK-2206, an Akt inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines

Akt 抑制剂 MK-2206 可增强卡铂/紫杉醇对胃癌细胞系的疗效

Khaldoun Almhanna, Christopher L Cubitt, Shumin Zhang, Sabiha Kazim, Kazim Husain, Daniel Sullivan, Said Sebti, Mokenge Malafa

CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo

CRM1 抑制剂可增强耐药性人类骨髓瘤细胞对拓扑异构酶 II 和蛋白酶体抑制剂的敏感性(无论是在体外还是在体内)

Joel G Turner, Jana Dawson, Michael F Emmons, Christopher L Cubitt, Michael Kauffman, Sharon Shacham, Lori A Hazlehurst, Daniel M Sullivan