日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pim Kinase Inhibitors Increase Gilteritinib Cytotoxicity in FLT3-ITD Acute Myeloid Leukemia Through GSK-3β Activation and c-Myc and Mcl-1 Proteasomal Degradation

Pim 激酶抑制剂通过 GSK-3β 激活以及 c-Myc 和 Mcl-1 蛋白酶体降解增加 Gilteritinib 在 FLT3-ITD 急性髓系白血病中的细胞毒性

Jonelle K Lee #, Aditi Chatterjee #, Mario Scarpa, Christopher M Bailey, Sandrine Niyongere, Prerna Singh, Moaath K Mustafa Ali, Shivani Kapoor, Yin Wang, Giovannino Silvestri, Maria R Baer

Targeting HIF-1α abrogates PD-L1-mediated immune evasion in tumor microenvironment but promotes tolerance in normal tissues

靶向 HIF-1α 可消除肿瘤微环境中 PD-L1 介导的免疫逃避,但可促进正常组织中的耐受性

Christopher M Bailey, Yan Liu, Mingyue Liu, Xuexiang Du, Martin Devenport, Pan Zheng, Yang Liu, Yin Wang

PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition-Dependent GSK-3β-Mediated c-Myc and Pim-1 Proteasomal Degradation

PP2A 激活药物通过 AKT 抑制依赖的 GSK-3β 介导的 c-Myc 和 Pim-1 蛋白酶体降解增强 FLT3 抑制剂的功效

Mario Scarpa, Prerna Singh, Christopher M Bailey, Jonelle K Lee, Shivani Kapoor, Rena G Lapidus, Sandrine Niyongere, Jaya Sangodkar, Yin Wang, Danilo Perrotti, Goutham Narla, Maria R Baer

Liposomal formulation of HIF-1α inhibitor echinomycin eliminates established metastases of triple-negative breast cancer

HIF-1α 抑制剂棘霉素的脂质体制剂可消除三阴性乳腺癌的已转移

Christopher M Bailey, Yan Liu, Gong Peng, Huixia Zhang, Miao He, Duxin Sun, Pan Zheng, Yang Liu, Yin Wang

Neutron-encoded mass signatures for quantitative top-down proteomics

用于定量自上而下蛋白质组学的中子编码质量特征

Rhoads, Timothy W; Rose, Christopher M; Bailey, Derek J; Riley, Nicholas M; Molden, Rosalynn C; Nestler, Amelia J; Merrill, Anna E; Smith, Lloyd M; Hebert, Alexander S; Westphall, Michael S; Pagliarini, David J; Garcia, Benjamin A; Coon, Joshua J

Common synaptic input to the human hypoglossal motor nucleus

人类舌下神经运动核的共同突触输入

Laine, Christopher M; Bailey, E Fiona

An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination

大肠杆菌 O157 中的大量 III 型分泌效应物以及类人噬菌体在其传播中的作用

Toru Tobe, Scott A Beatson, Hisaaki Taniguchi, Hiroyuki Abe, Christopher M Bailey, Amanda Fivian, Rasha Younis, Sophie Matthews, Olivier Marches, Gad Frankel, Tetsuya Hayashi, Mark J Pallen