日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis

基因操纵体内内源性 Kras 水平和致癌突变影响小鼠肿瘤发生的组织模式

Özgün Le Roux, Nicole L K Pershing, Erin Kaltenbrun, Nicole J Newman, Jeffrey I Everitt, Elisa Baldelli, Mariaelena Pierobon, Emanuel F Petricoin, Christopher M Counter

An ultra-sensitive method to detect mutations in human RAS templates

一种检测人类 RAS 模板突变的超灵敏方法

Siqi Li, Christopher M Counter

Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity

致癌基因 KRAS 依赖 EFR3A-PI4KA 信号轴发挥强效致瘤活性

Hema Adhikari, Walaa E Kattan, Shivesh Kumar, Pei Zhou, John F Hancock, Christopher M Counter

Signaling levels mold the RAS mutation tropism of urethane

信号水平决定了氨基甲酸酯的 RAS 突变趋向性

Siqi Li, Christopher M Counter

Using BioID to Characterize the RAS Interactome

使用 BioID 来表征 RAS 相互作用组

Hema Adhikari, Christopher M Counter

Expression of transgenes enriched in rare codons is enhanced by the MAPK pathway

MAPK 通路增强富含稀有密码子的转基因表达

Jackson Peterson, Siqi Li, Erin Kaltenbrun, Ozgun Erdogan, Christopher M Counter

Exploiting codon usage identifies intensity-specific modifiers of Ras/MAPK signaling in vivo

利用密码子的使用来识别体内 Ras/MAPK 信号的强度特异性修饰物

Jessica K Sawyer, Zahra Kabiri, Ruth A Montague, Scott R Allen, Rebeccah Stewart, Sarah V Paramore, Erez Cohen, Hamed Zaribafzadeh, Christopher M Counter, Donald T Fox

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability

通过研究 RAS 亚型的蛋白质相互作用组,可以确定 PIP5K1A 是 KRAS 特有的弱点

Hema Adhikari, Christopher M Counter

Copper Chelation as Targeted Therapy in a Mouse Model of Oncogenic BRAF-Driven Papillary Thyroid Cancer

铜螯合物作为致癌 BRAF 驱动的乳头状甲状腺癌小鼠模型的靶向治疗

MengMeng Xu, Michael Casio, Danielle E Range, Julie A Sosa, Christopher M Counter

Wild-type Kras expands and exhausts hematopoietic stem cells

野生型Kras会扩增并消耗造血干细胞。

Joshua P Sasine ,Heather A Himburg ,Christina M Termini ,Martina Roos ,Evelyn Tran ,Liman Zhao ,Jenny Kan ,Michelle Li ,Yurun Zhang ,Stéphanie C de Barros ,Dinesh S Rao ,Christopher M Counter ,John P Chute