Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera.
VHL募集嵌合体通过化学方法诱导内质网应激传感器IRE1的降解。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66382-8
Du Jin, Villemure Elisia, Johnson Matthew, Azumaya Caleigh, Gaspar Catarina J, Marsters Scot, Lawrence David, Foster Scott, Rohou Alexis, Cheung Tommy K, Rose Christopher M, Garner Thomas, Ro Soo, Clark Kevin, Beresini Maureen H, Braun Marie-Gabrielle, Rudolph Joachim, Hsu Peter, Ashkenazi Avi
