日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function.

P21激活激酶-1信号传导对于维持脂肪组织稳态和心脏功能是必需的

Munoz Marcos, Solis Christopher, McCann Maximilian, Park Jooman, Rafael-Clyke Koreena, Chowdhury Shamim A K, Jiang Yuwei, Rosas Paola C

Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer

IAP 拮抗剂 Tolinapant (ASTX660) 在结直肠癌中的临床定位

Nyree Crawford, Katie J Stott, Tamas Sessler, Christopher McCann, William McDaid, Andrea Lees, Cheryl Latimer, Jennifer P Fox, Joanne M Munck, Tomoko Smyth, Alpesh Shah, Vanessa Martins, Mark Lawler, Philip D Dunne, Emma M Kerr, Simon S McDade, Vicky M Coyle, Daniel B Longley

Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

结肠癌细胞对 SMAC 类似物 Birinapant 的分子亚型特异性反应

Michael Fichtner, Emir Bozkurt, Manuela Salvucci, Christopher McCann, Katherine A McAllister, Luise Halang, Heiko Düssmann, Sinéad Kinsella, Nyree Crawford, Tamas Sessler, Daniel B Longley, Jochen H M Prehn

A revised model of TRAIL-R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis

TRAIL-R2 DISC 组装的修订模型解释了 FLIP(L) 如何抑制或促进细胞凋亡

Luke M Humphreys, Jennifer P Fox, Catherine A Higgins, Joanna Majkut, Tamas Sessler, Kirsty McLaughlin, Christopher McCann, Jamie Z Roberts, Nyree T Crawford, Simon S McDade, Christopher J Scott, Timothy Harrison, Daniel B Longley

Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists

细胞质 FLIP(S) 和核 FLIP(L) 介导去势抵抗性前列腺癌对 IAP 拮抗剂诱导的细胞凋亡的抵抗

Christopher McCann, Nyree Crawford, Joanna Majkut, Caitriona Holohan, Chris W D Armstrong, Pamela J Maxwell, Chee Wee Ong, Melissa J LaBonte, Simon S McDade, David J Waugh, Daniel B Longley

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy

PTEN 缺陷促进巨噬细胞浸润和前列腺癌对 IAP 拮抗剂/放射联合治疗的高敏感性

Chris W D Armstrong, Pamela J Maxwell, Chee Wee Ong, Kelly M Redmond, Christopher McCann, Jessica Neisen, George A Ward, Gianni Chessari, Christopher Johnson, Nyree T Crawford, Melissa J LaBonte, Kevin M Prise, Tracy Robson, Manuel Salto-Tellez, Daniel B Longley, David J J Waugh