Christopher N Mayhew相关文献与解析，生知库

Holly M Poling ，Nambirajan Sundaram ，Garrett W Fisher ，Akaljot Singh ，Joseph R Shiley ，Kalpana Nattamai ，Vinothini Govindarajah ，Alexander R Cortez ，Maksym O Krutko ，Séverine Ménoret ，Ignacio Anegon ，Magdalena Kasendra ，James M Wells ，Christopher N Mayhew ，Takanori Takebe ，Maxime M Mahe ，Michael A Helmrath

细胞生物学

3D/类器官

发育与干细胞

Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate

Pioneer 和 PRDM 转录因子协调二价表观遗传状态，以保障细胞命运

期刊:Molecular Cell

影响因子:14.5

doi:10.1016/j.molcel.2023.12.007

Satoshi Matsui ,Marissa Granitto ,Morgan Buckley ,Katie Ludwig ,Sandra Koigi ,Joseph Shiley ,William J Zacharias ,Christopher N Mayhew ,Hee-Woong Lim ,Makiko Iwafuchi

Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells

建立可诱导型 CRISPRd 系统以阻断人类多能干细胞中转录因子结合位点的方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2024.103233

Satoshi Matsui,Joseph R Shiley,Morgan Buckley,Hee-Woong Lim,Yueh-Chiang Hu,Christopher N Mayhew,Makiko Iwafuchi

Protocol for establishing inducible CRISPR interference system for multiple-gene silencing in human pluripotent stem cells

建立可诱导的 CRISPR 干扰系统用于人类多能干细胞多基因沉默的方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2024.103221

Satoshi Matsui, Joseph R Shiley, Marissa Granitto, Katie Ludwig, Morgan Buckley, Sandra Koigi, Gerardo Mirizio, Yueh-Chiang Hu, Christopher N Mayhew, Makiko Iwafuchi

Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon

人类多能干细胞来源的结肠类器官和人类胎儿结肠中功能性驻留巨噬细胞的发育

期刊:Cell Stem Cell

影响因子:19.8

doi:10.1016/j.stem.2023.10.002

Jorge O Múnera ，Daniel O Kechele ，Carine Bouffi ，Na Qu ，Ran Jing ，Pritiprasanna Maity ，Jacob R Enriquez ，Lu Han ，Ian Campbell ，Maxime M Mahe ，Heather A McCauley ，Xinghao Zhang ，Nambirajan Sundaram ，Jonathan R Hudson ，Adrian Zarsozo-Lacoste ，Suman Pradhan ，Kentaro Tominaga ，J Guillermo Sanchez ，Alison A Weiss ，Praneet Chatuvedi ，Jason R Spence ，Mariam Hachimi ，Trista North ，George Q Daley ，Christopher N Mayhew ，Yueh-Chiang Hu ，Takanori Takebe ，Michael A Helmrath ，James M Wells

A review of protocols for brain organoids and applications for disease modeling

脑类器官的方案和疾病建模应用的回顾

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2022.101860

Christopher N Mayhew, Richa Singhania

细胞生物学

发表日期：2023

文献求助收藏

iPSC-derived neural precursor cells engineering GBA1 recovers acid β-glucosidase deficiency and diminishes α-synuclein and neuropathology

iPSC 衍生的神经前体细胞工程 GBA1 可恢复酸性 β-葡萄糖苷酶缺乏症并减少 α-突触核蛋白和神经病理学

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:

doi:10.1016/j.omtm.2023.03.007

Yanyan Peng, Benjamin Liou, Yi Lin, Christopher N Mayhew, Sheila M Fleming, Ying Sun

Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency

人类 iPSC 衍生的肝细胞系统模拟紧密连接蛋白 2 缺乏导致的胆汁淤积

期刊:Jhep Reports

影响因子:9.5

doi:10.1016/j.jhepr.2022.100446

Chao Zheng Li, Hiromi Ogawa, Soon Seng Ng, Xindi Chen, Eriko Kishimoto, Kokoro Sakabe, Aiko Fukami, Yueh-Chiang Hu, Christopher N Mayhew, Jennifer Hellmann, Alexander Miethke, Nahrin L Tasnova, Samuel J I Blackford, Zu Ming Tang, Adam M Syanda, Liang Ma, Fang Xiao, Melissa Sambrotta, Oliver Tavabie,

Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation

聚集冷冻保存的中后肠内胚层，以获得更可靠、可重复的 hPSC 衍生小肠类器官生成

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2022.06.011

Amy L Pitstick, Holly M Poling, Nambirajan Sundaram, Phillip L Lewis, Daniel O Kechele, J Guillermo Sanchez, Melissa A Scott, Taylor R Broda, Michael A Helmrath, James M Wells, Christopher N Mayhew

信号转导

发表日期：2022

文献求助收藏

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids

利用iPSC衍生的人类肠道类器官对CFTR和其他顶端定位蛋白进行高通量功能分析

期刊:Cells

影响因子:5.1

doi:10.3390/cells10123419

Sunny Xia ，Zoltán Bozóky ，Michelle Di Paola ，Onofrio Laselva ，Saumel Ahmadi ，Jia Xin Jiang ，Amy L Pitstick ，Chong Jiang ，Daniela Rotin ，Christopher N Mayhew ，Nicola L Jones ，Christine E Bear

Human pluripotent stem cell-derived organoids repair damaged bowel in vivo

人类多能干细胞衍生的类器官可在体内修复受损肠道

Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate

Pioneer 和 PRDM 转录因子协调二价表观遗传状态，以保障细胞命运

Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells

建立可诱导型 CRISPRd 系统以阻断人类多能干细胞中转录因子结合位点的方案

Protocol for establishing inducible CRISPR interference system for multiple-gene silencing in human pluripotent stem cells

建立可诱导的 CRISPR 干扰系统用于人类多能干细胞多基因沉默的方案

Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon

人类多能干细胞来源的结肠类器官和人类胎儿结肠中功能性驻留巨噬细胞的发育

A review of protocols for brain organoids and applications for disease modeling

脑类器官的方案和疾病建模应用的回顾

iPSC-derived neural precursor cells engineering GBA1 recovers acid β-glucosidase deficiency and diminishes α-synuclein and neuropathology

iPSC 衍生的神经前体细胞工程 GBA1 可恢复酸性 β-葡萄糖苷酶缺乏症并减少 α-突触核蛋白和神经病理学

Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency

人类 iPSC 衍生的肝细胞系统模拟紧密连接蛋白 2 缺乏导致的胆汁淤积

Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation

聚集冷冻保存的中后肠内胚层，以获得更可靠、可重复的 hPSC 衍生小肠类器官生成

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids

利用iPSC衍生的人类肠道类器官对CFTR和其他顶端定位蛋白进行高通量功能分析