日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibiotic-resistance mutations in penicillin-binding protein 2 from the ceftriaxone-resistant Neisseria gonorrhoeae strain H041 strike a delicate balance between increasing resistance and maintaining transpeptidase activity

来自耐头孢曲松淋病奈瑟菌H041株的青霉素结合蛋白2的抗生素耐药突变,在增强耐药性和维持转肽酶活性之间维持着微妙的平衡。

Bivins, Marissa M; Tomberg, Joshua; Bagshaw, Madeleine; Singh, Avinash; Bala, Sandeepchowdary; Davies, Christopher; Nicholas, Robert A

Antibiotic-resistance mutations in penicillin-binding protein 2 from the ceftriaxone-resistant Neisseria gonorrhoeae strain H041 strike a delicate balance between increasing resistance and maintaining transpeptidase activity

来自耐头孢曲松淋病奈瑟菌H041株的青霉素结合蛋白2的抗生素耐药突变,在增强耐药性和维持转肽酶活性之间维持着微妙的平衡。

Bivins, Marissa M; Tomberg, Joshua; Bagshaw, Madeleine; Singh, Avinash; Bala, Sandeepchowdary; Davies, Christopher; Nicholas, Robert A

Employing zero-inflated beta distribution in an exposure-response analysis of TYK2/JAK1 inhibitor brepocitinib in patients with plaque psoriasis

在斑块状银屑病患者中,采用零膨胀β分布对TYK2/JAK1抑制剂brepocitinib进行暴露-反应分析

Tsamandouras, Nikolaos; Qiu, Ruolun; Hughes, Jim H; Sweeney, Kevin; Prybylski, John P; Banfield, Christopher; Nicholas, Timothy

A systematic review of the biomechanical properties of suture materials used in orthopaedics

对骨科缝合材料生物力学特性的系统评价

Perez, Andres R; Coladonato, Carlo; Muchintala, Rahul; Christopher, Nicholas; Matthews, John; Tjoumakaris, Fotios P; Freedman, Kevin B

Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development

利特西替尼群体药代动力学模型在临床药物研发过程中的演变

Wojciechowski, Jessica; S Purohit, Vivek; Huh, Yeamin; Banfield, Christopher; Nicholas, Timothy

Combined HPV 16 E2 and L1 methylation predict response to treatment with cidofovir and imiquimod in patients with vulval intraepithelial neoplasia

HPV 16 E2 和 L1 甲基化联合检测可预测外阴上皮内瘤变患者对西多福韦和咪喹莫特治疗的反应

Hurt, Christopher Nicholas; Nedjai, Belinda; Alvarez-Mendoza, Carlos; Powell, Ned; Tristram, Amanda; Jones, Sadie

Cutaneous Lupus Erythematosus: Progress and Challenges

皮肤型红斑狼疮:进展与挑战

Petty, Amy J; Floyd, Lauren; Henderson, Christopher; Nicholas, Matilda W

NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma

NEOSCOPE:一项随机II期研究,比较诱导化疗后序贯奥沙利铂/卡培他滨或卡铂/紫杉醇方案的术前放化疗治疗可切除食管腺癌的疗效

Mukherjee, Somnath; Hurt, Christopher Nicholas; Gwynne, Sarah; Sebag-Montefiore, David; Radhakrishna, Ganesh; Gollins, Simon; Hawkins, Maria; Grabsch, Heike I; Jones, Gareth; Falk, Stephen; Sharma, Ricky; Bateman, Andrew; Roy, Rajarshi; Ray, Ruby; Canham, Jo; Griffiths, Gareth; Maughan, Tim; Crosby, Tom

Neutrophil gelatinase-associated lipocalin prior to cardiac surgery predicts acute kidney injury and mortality

心脏手术前中性粒细胞明胶酶相关脂质运载蛋白水平可预测急性肾损伤和死亡率

Bulluck, Heerajnarain; Maiti, Raju; Chakraborty, Bibhas; Candilio, Luciano; Clayton, Tim; Evans, Richard; Jenkins, David P; Kolvekar, Shyam; Kunst, Gudrun; Laing, Christopher; Nicholas, Jennifer; Pepper, John; Yellon, Derek M; Hausenloy, Derek J

Identification of amino acids conferring high-level resistance to expanded-spectrum cephalosporins in the penA gene from Neisseria gonorrhoeae strain H041

从淋病奈瑟菌H041株的penA基因中鉴定出赋予其对广谱头孢菌素高水平耐药性的氨基酸

Tomberg, Joshua; Unemo, Magnus; Ohnishi, Makoto; Davies, Christopher; Nicholas, Robert A