日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models

替莫唑胺不会损害同基因脑肿瘤模型中基因治疗介导的抗肿瘤免疫力

Marianela Candolfi #, Kader Yagiz #, Mia Wibowo, Gabrielle E Ahlzadeh, Mariana Puntel, Homayon Ghiasi, Neha Kamran, Christopher Paran, Pedro R Lowenstein, Maria G Castro

Marmosets as a preclinical model for testing "off-label" use of doxycycline to turn on Flt3L expression from high-capacity adenovirus vectors

狨猴作为临床前模型,用于测试“标签外”使用强力霉素来开启高容量腺病毒载体的 Flt3L 表达

Nathan VanderVeen, Christopher Paran, Ashley Appelhans, Johnny Krasinkiewicz, Rosemary Lemons, Henry Appelman, Robert Doherty, Donna Palmer, Philip Ng, Pedro R Lowenstein, Maria G Castro

Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastoma

编码免疫刺激和细胞毒性基因治疗的双顺反子高容量腺病毒载体的安全性、有效性和生物分布作为胶质母细胞瘤 I 期临床试验的前奏

Mariana Puntel, Ghulam Muhammad A K M, Catherine Farrokhi, Nathan Vanderveen, Christopher Paran, Ashley Appelhans, Kurt M Kroeger, Alireza Salem, Liliana Lacayo, Robert N Pechnick, Kyle R Kelson, Sukhpreet Kaur, Sean Kennedy, Donna Palmer, Philip Ng, Chunyan Liu, Johnny Krasinkiewicz, Pedro R Lowens

High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins

肥胖患者肌肉脂质含量高并不是由于关键甘油三酸酯酯化酶的活性增强或脂肪分解蛋白的抑制

Minghua Li, Christopher Paran, Nathan E Wolins, Jeffrey F Horowitz