Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors
利用 CYP2D6 和 BACE1 复合物的结构，通过一系列新型中枢有效 BACE1 抑制剂降低药物相互作用的风险
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5b00191
Michael A Brodney, Elizabeth M Beck, Christopher R Butler, Gabriela Barreiro, Eric F Johnson, David Riddell, Kevin Parris, Charles E Nolan, Ying Fan, Kevin Atchison, Cathleen Gonzales, Ashley E Robshaw, Shawn D Doran, Mark W Bundesmann, Leanne Buzon, Jason Dutra, Kevin Henegar, Erik LaChapelle, Xinj
