日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.

PIP4K2C 抑制可逆转 SARS-CoV-2 引起的自噬通量受损

Karim Marwah, Mishra Manjari, Lo Chieh-Wen, Saul Sirle, Cagirici Halise Busra, Gourdelier Manon, Ghita Luca, Ojha Amrita, Tran Do Hoang Nhu, Agrawal Aditi, McGraw Connor, East Michael P, Gammeltoft Karen Anbro, Sahoo Malaya Kumar, Mooney Nancie A, Johnson Gary L, Das Soumita, Leyssen Pieter, Neyts Johan, Chiu Winston, Cohen Courtney A, Bukh Jens, Gottwein Judith, Dye John M, Neff Norma, Jackson Peter K, Pinsky Benjamin A, Laitinen Tuomo, Pantsar Tatu, Poso Antti, Zanini Fabio, De Jonghe Steven, Asquith Christopher R M, Einav Shirit

Vehicle Age and Driver Assistance Technologies in Fatal Crashes Involving Teen and Middle-Aged Drivers

车辆年龄和驾驶辅助技术在涉及青少年和中年驾驶员的致命车祸中的作用

Zhang, Fangda; Rundus, Christopher R M; Alshaikh, Enas; Peek-Asa, Corinne; Yang, Jingzhen

Enhancing colistin efficacy against Salmonella infections with a quinazoline-based dual therapeutic strategy.

利用喹唑啉类双重治疗策略增强粘菌素对沙门氏菌感染的疗效

Lobertti Carlos A, Gizzi Fernán O, Magni Christian, Rial Analía, Chabalgoity José A, Yim Lucía, Blancato Víctor S, Asquith Christopher R M, García Véscovi Eleonora

Pentathiepins are an understudied molecular prism of biological activities

五硫杂环庚烷是一类尚未得到充分研究的生物活性分子棱镜

Pozzetti, Luca; Asquith, Christopher R M

Small-molecule inhibition of the archetypal UbiB protein COQ8

小分子抑制原型UbiB蛋白COQ8

Nathan H Murray, Christopher R M Asquith, Zixiang Fang, Michael P East, Naomi Ptak, Robert W Smith, James D Vasta, Chad A Zimprich, Cesear R Corona, Matthew B Robers, Gary L Johnson, Craig A Bingman, David J Pagliarini

The Synthesis and Biological Applications of the 1,2,3-Dithiazole Scaffold

1,2,3-二噻唑骨架的合成及其生物学应用

Kalogirou, Andreas S; Oh, Hans J; Asquith, Christopher R M

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies

Numb 相关激酶是 SARS-CoV-2 感染所必需的,也是抗病毒策略的细胞靶标

Marwah Karim, Sirle Saul, Luca Ghita, Malaya Kumar Sahoo, Chengjin Ye, Nishank Bhalla, Chieh-Wen Lo, Jing Jin, Jun-Gyu Park, Belén Martinez-Gualda, Michael Patrick East, Gary L Johnson, Benjamin A Pinsky, Luis Martinez-Sobrido, Christopher R M Asquith, Aarthi Narayanan, Steven De Jonghe, Shirit Eina

Identification of 4-Anilinoquin(az)oline as a Cell-Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype

鉴定 4-苯胺基喹啉(唑)啉为细胞活性蛋白激酶新型 3 (PKN3) 抑制剂化学型

Asquith, Christopher R M; Temme, Louisa; East, Michael P; Laitinen, Tuomo; Pickett, Julie; Kwarcinski, Frank E; Sinha, Parvathi; Wells, Carrow I; Johnson, Gary L; Zutshi, Reena; Drewry, David H

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

铰链结合剂支架跳跃可识别强效钙/钙调蛋白依赖性蛋白激酶激酶 2 (CAMKK2) 抑制剂化学型

Benjamin J Eduful, Sean N O'Byrne, Louisa Temme, Christopher R M Asquith, Yi Liang, Alfredo Picado, Joseph R Pilotte, Mohammad Anwar Hossain, Carrow I Wells, William J Zuercher, Carolina M C Catta-Preta, Priscila Zonzini Ramos, André de S Santiago, Rafael M Couñago, Christopher G Langendorf, Kévin N

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

铰链结合剂支架跳跃鉴定出强效的钙/钙调蛋白依赖性蛋白激酶激酶2 (CAMKK2) 抑制剂化学类型

Benjamin J Eduful,Sean N O'Byrne,Louisa Temme,Christopher R M Asquith,Yi Liang,Alfredo Picado,Joseph R Pilotte,Mohammad Anwar Hossain,Carrow I Wells,William J Zuercher,Carolina M C Catta-Preta,Priscila Zonzini Ramos,André de S Santiago,Rafael M Couñago,Christopher G Langendorf,Kévin Nay,Jonathan S Oakhill,Thomas L Pulliam ,Chenchu Lin,Dominik Awad,Timothy M Willson,Daniel E Frigo ,John W Scott ,David H Drewry