Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1
硼替佐米在骨髓增生异常综合征/急性髓系白血病中的细胞毒性作用依赖于自噬介导的溶酶体 TRAF6 降解和 PSMA1 抑制
期刊:Blood
影响因子:21
doi:10.1182/blood-2012-02-407999
Jing Fang, Garrett Rhyasen, Lyndsey Bolanos, Christopher Rasch, Melinda Varney, Mark Wunderlich, Susumu Goyama, Gerrit Jansen, Jacqueline Cloos, Carmela Rigolino, Agostino Cortelezzi, James C Mulloy, Esther N Oliva, Maria Cuzzola, Daniel T Starczynowski
信号转导
肿瘤
白血病
其它细胞
FCM
IF
IHC-P
WB
Autophagy
