Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination
对严重联合免疫缺陷症 (SCID) 和奥门综合征 (Omenn syndrome) 患者的突变进行分析,揭示了 Rag2 PHD 结构域在调节 V(D)J 重组中的核心作用
期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI41305
Chrystelle Couëdel, Christopher Roman, Alison Jones, Paolo Vezzoni, Anna Villa, Patricia Cortes