日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer's disease

通过限时喂养进行昼夜节律调节可挽救阿尔茨海默病小鼠模型的脑部病理并改善记忆力

Daniel S Whittaker, Laila Akhmetova, Daniel Carlin, Haylie Romero, David K Welsh, Christopher S Colwell, Paula Desplats

Motor Activity-Induced White Matter Repair in White Matter Stroke

白质中风时运动活动诱发的白质修复

Miguel A Marin, Amy J Gleichman, Xiaofei Wei, Daniel S Whittaker, Istvan Mody, Christopher S Colwell, S Thomas Carmichael

Activation of mGluR1 negatively modulates glutamate-induced phase shifts of the circadian pacemaker in the mouse suprachiasmatic nucleus

mGluR1 的激活会负向调节小鼠视交叉上核中谷氨酸诱导的昼夜节律起搏器相移

Yoon Sik Kim, C Justin Lee, Ji-Hyeon Kim, Young-Beom Kim, Christopher S Colwell, Yang In Kim

Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice

不间断的CAG重复序列驱动人类亨廷顿蛋白BAC小鼠纹状体选择性转录病变和核病变

Xiaofeng Gu ,Jeffrey Richman ,Peter Langfelder ,Nan Wang ,Shasha Zhang ,Monica Bañez-Coronel ,Huei-Bin Wang ,Lucia Yang ,Lalini Ramanathan ,Linna Deng ,Chang Sin Park ,Christopher R Choi ,Jeffrey P Cantle ,Fuying Gao ,Michelle Gray ,Giovanni Coppola ,Gillian P Bates ,Laura P W Ranum ,Steve Horvath ,Christopher S Colwell ,X William Yang

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function

限时喂养可通过表观遗传控制 β 细胞功能来防止昼夜节律紊乱造成的有害代谢影响

Matthew R Brown, Satish K Sen, Amelia Mazzone, Tracy K Her, Yuning Xiong, Jeong-Heon Lee, Naureen Javeed, Christopher S Colwell, Kuntol Rakshit, Nathan K LeBrasseur, Alexandre Gaspar-Maia, Tamas Ordog, Aleksey V Matveyenko

Oestrogen inhibits salt-dependent hypertension by suppressing GABAergic excitation in magnocellular AVP neurons

雌激素通过抑制大细胞 AVP 神经元中的 GABA 能兴奋来抑制盐依赖性高血压

Xiangyan Jin, Woong Bin Kim, Mi-Na Kim, Won Woo Jung, Hyung Kyung Kang, Eun-Hwa Hong, Yoon Sik Kim, Wan Joo Shim, Hee Chul Han, Christopher S Colwell, Young-Beom Kim, Yang In Kim

Targeted Genetic Reduction of Mutant Huntingtin Lessens Cardiac Pathology in the BACHD Mouse Model of Huntington's Disease

针对性地减少突变型亨廷顿蛋白可减轻亨廷顿病 BACHD 小鼠模型中的心脏病理

Saemi Park, Shu Hon Christopher Luk, Raj S Bains, Daniel S Whittaker, Emily Chiem, Maria C Jordan, Kenneth P Roos, Cristina A Ghiani, Christopher S Colwell

Postnatal Ontogenesis of the Islet Circadian Clock Plays a Contributory Role in β-Cell Maturation Process

出生后胰岛生物钟的个体发生对 β 细胞成熟过程起着促进作用

Kuntol Rakshit, Jingyi Qian, Krutika Satish Gaonkar, Sangeeta Dhawan, Christopher S Colwell, Aleksey V Matveyenko

Sex Differences in Circadian Dysfunction in the BACHD Mouse Model of Huntington's Disease

亨廷顿氏病 BACHD 小鼠模型中昼夜节律紊乱的性别差异

Dika A Kuljis, Laura Gad, Dawn H Loh, Zoë MacDowell Kaswan, Olivia N Hitchcock, Cristina A Ghiani, Christopher S Colwell

Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease

亨廷顿氏病 BACHD 小鼠模型中的心脏功能障碍

Analyne M Schroeder, Huei Bin Wang, Saemi Park, Maria C Jordan, Fuying Gao, Giovanni Coppola, Michael C Fishbein, Kenneth P Roos, Cristina A Ghiani, Christopher S Colwell