日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks

FRA1 (FOSL1) 通过转录调控促有丝分裂和应激反应网络,抑制肿瘤转化并调节辐射反应。

Wuroud Al-Khayyat ,Taylor Laframboise ,Jessica Dougherty ,Marc S Mendonca ,Douglas R Boreham ,T C Tai ,Christopher Thome ,Sujeenthar Tharmalingam

Molecular Adaptations to Repeated Radiation Exposure in Triple-Negative Breast Cancer: Dysregulation of Cell Adhesion, Mitochondrial Function, and Epithelial-Mesenchymal Transition

三阴性乳腺癌对重复辐射暴露的分子适应:细胞粘附、线粒体功能和上皮-间质转化的失调

Noah Dickinson ,Alyssa Murray ,Megan Davis ,Kaitlyn Marshall-Bergeron ,Jessica Dougherty ,Wuroud Al-Khayyat ,Ramya Narendrula ,Maggie Lavoie ,Emma Mageau ,Ronan Derbowka ,A Thomas Kovala ,Douglas R Boreham ,Natalie Lefort ,Christopher Thome ,Tze Chun Tai ,Sujeenthar Tharmalingam

Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression

FRA1(FOSL1)的过度表达会导致整体转录紊乱、细胞粘附性降低和细胞周期进程改变。

Wuroud Al-Khayyat ,Jake Pirkkanen ,Jessica Dougherty ,Taylor Laframboise ,Noah Dickinson ,Neelam Khaper ,Simon J Lees ,Marc S Mendonca ,Douglas R Boreham ,Tze Chun Tai ,Christopher Thome ,Sujeenthar Tharmalingam

Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo

辐射诱导的人类CGL1细胞肿瘤转化过程中FOSL1肿瘤抑制基因的基因组丢失和表观遗传沉默改变了体外和体内的致瘤表型

Jake Pirkkanen,Sujeenthar Tharmalingam,Christopher Thome,Helen Chin Sinex,Laura V Benjamin,Adam C Losch,Anthony J Borgmann,Ryan M Dhaemers,Christopher Gordon,Douglas R Boreham,Marc S Mendonca

Identification of Radiation-Induced miRNA Biomarkers Using the CGL1 Cell Model System

使用 CGL1 细胞模型系统鉴定辐射诱导的 miRNA 生物标志物

Jayden Peterson, Christopher D McTiernan, Christopher Thome, Neelam Khaper, Simon J Lees, Douglas R Boreham, Tze Chun Tai, Sujeenthar Tharmalingam

Radiation-Induced Alterations in Proliferation, Migration, and Adhesion in Lens Epithelial Cells and Implications for Cataract Development

辐射诱导晶状体上皮细胞增殖、迁移和粘附的改变及其对白内障发展的影响

Graysen Vigneux, Jake Pirkkanen, Taylor Laframboise, Hallie Prescott, Sujeenthar Tharmalingam, Christopher Thome