日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Acute microtubule changes linked to DMD pathology are insufficient to impair contractile function or enhance contraction-induced injury in healthy muscle

与 DMD 病理相关的急性微管变化不足以损害收缩功能或增强健康肌肉的收缩诱发损伤

Camilo Vanegas, Jeanine Ursitti, Jacob G Kallenbach, Kaylie Pinto, Anicca Harriot, Andrew K Coleman, Guoli Shi, Christopher W Ward

Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers

去酪氨酸化的微管阵列导致 mdx 肌纤维中的肌原纤维畸形

Anicca D Harriot, Tessa Altair Morris, Camilo Vanegas, Jacob Kallenbach, Kaylie Pinto, Humberto C Joca, Marie-Jo Moutin, Guoli Shi, Jeanine A Ursitti, Anna Grosberg, Christopher W Ward

Voltage sensor current, SR Ca2+ release, and Ca2+ channel current during trains of action potential-like depolarizations of skeletal muscle fibers

骨骼肌纤维动作电位样去极化过程中的电压传感器电流、SR Ca2+ 释放和 Ca2+ 通道电流

Hugo Bibollet, Elton L Nguyen, Daniel R Miranda, Christopher W Ward, Andrew A Voss, Martin F Schneider, Erick O Hernández-Ochoa

Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy

骨骼肌卫星细胞的消耗可减轻肌营养不良症的病理

Justin G Boyer, Jiuzhou Huo, Sarah Han, Julian R Havens, Vikram Prasad, Brian L Lin, David A Kass, Taejeong Song, Sakthivel Sadayappan, Ramzi J Khairallah, Christopher W Ward, Jeffery D Molkentin

Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy

药理学 TRPC6 抑制可改善杜氏肌营养不良症小鼠的生存率和肌肉功能

Brian L Lin, Joseph Y Shin, William Pd Jeffreys, Nadan Wang, Clarisse A Lukban, Megan C Moorer, Esteban Velarde, Olivia A Hanselman, Seoyoung Kwon, Suraj Kannan, Ryan C Riddle, Christopher W Ward, Steven S Pullen, Antonio Filareto, David A Kass

Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice

两种运动训练方案对雄性小鼠骨骼肌和肝脏基因组及代谢重塑的年龄依赖性影响

Michel Bernier # ,Ignacio Navas Enamorado # ,Mari Carmen Gómez-Cabrera # ,Miguel Calvo-Rubio ,Jose Antonio González-Reyes ,Nathan L Price ,Ana Belén Cortés-Rodríguez ,Juan Carlos Rodríguez-Aguilera ,Sandra Rodríguez-López ,Sarah J Mitchell ,Kelsey N Murt ,Krystle Kalafut ,Katrina M Williams ,Christopher W Ward ,Joseph P Stains ,Gloria Brea-Calvo ,Jose M Villalba ,Sonia Cortassa # ,Miguel A Aon # ,Rafael de Cabo

Disparate bone anabolic cues activate bone formation by regulating the rapid lysosomal degradation of sclerostin protein

不同的骨合成代谢线索通过调节骨硬化蛋白的溶酶体快速降解来激活骨形成

Nicole R Gould, Katrina M Williams, Humberto C Joca, Olivia M Torre, James S Lyons, Jenna M Leser, Manasa P Srikanth, Marcus Hughes, Ramzi J Khairallah, Ricardo A Feldman, Christopher W Ward, Joseph P Stains

Attenuating persistent sodium current-induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress

通过预防线粒体氧化应激减轻持续性钠电流诱发的心房肌病和房颤

Uma Mahesh R Avula, Haikel Dridi, Bi-Xing Chen, Qi Yuan, Alexander N Katchman, Steven R Reiken, Amar D Desai, Samantha Parsons, Haajra Baksh, Elaine Ma, Parmanand Dasrat, Ruiping Ji, Yejun Lin, Christine Sison, W Jonathan Lederer, Humberto C Joca, Christopher W Ward, Maura Greiser, Andrew R Marks, S

Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle

微管蛋白乙酰化增加细胞骨架硬度以调节横纹肌的机械转导

Andrew K Coleman #, Humberto C Joca #, Guoli Shi, W Jonathan Lederer, Christopher W Ward

μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism

小鼠骨骼肌中的 μ-晶体蛋白促进糖酵解向氧化代谢的转变

Christian J Kinney, Andrea O'Neill, Kaila Noland, Weiliang Huang, Joaquin Muriel, Valeriy Lukyanenko, Maureen A Kane, Christopher W Ward, Alyssa F Collier, Joseph A Roche, John C McLenithan, Patrick W Reed, Robert J Bloch