Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease
BSN 中的蛋白质截短变异与成人重度肥胖、2 型糖尿病和脂肪肝疾病相关。
期刊:Nature Genetics
影响因子:29
doi:10.1038/s41588-024-01694-x
Zhao, Yajie; Chukanova, Maria; Kentistou, Katherine A; Fairhurst-Hunter, Zammy; Siegert, Anna Maria; Jia, Raina Y; Dowsett, Georgina K C; Gardner, Eugene J; Lawler, Katherine; Day, Felix R; Kaisinger, Lena R; Tung, Yi-Chun Loraine; Lam, Brian Yee Hong; Chen, Hsiao-Jou Cortina; Wang, Quanli; Berumen-Campos, Jaime; Kuri-Morales, Pablo; Tapia-Conyer, Roberto; Alegre-Diaz, Jesus; Barroso, Inês; Emberson, Jonathan; Torres, Jason M; Collins, Rory; Saleheen, Danish; Smith, Katherine R; Paul, Dirk S; Merkle, Florian; Farooqi, I Sadaf; Wareham, Nick J; Petrovski, Slavé; O'Rahilly, Stephen; Ong, Ken K; Yeo, Giles S H; Perry, John R B
