日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functionally heterogeneous intratumoral CD4(+)CD8(+) double-positive T cells can give rise to single-positive T cells

功能异质性的肿瘤内CD4(+)CD8(+)双阳性T细胞可以分化为单阳性T细胞。

Li, Tony; Ilano, Arielle; Arias-Badia, Marcel; Luong, Diamond; Chang, Hewitt; Kwek, Serena S; Allaire, Kathryn; Chumber, Arun; Sakamoto, Mason; Clark, Matthew; Lea, Averey; Bridge, Mark; Chen, Brandon; Liu, Eric; Porten, Sima; Meng, Maxwell V; Erlich, Lauren I R; Oh, David Y; Fong, Lawrence

Phase I, First-in-Human Study of FOR46 (FG-3246), an Immune-Modulating Antibody-Drug Conjugate Targeting CD46, in Patients With Metastatic Castration-Resistant Prostate Cancer

FOR46 (FG-3246) 是一种靶向 CD46 的免疫调节抗体药物偶联物,用于治疗转移性去势抵抗性前列腺癌患者,这是一项 I 期首次人体研究。

Aggarwal, Rahul R; Vuky, Jacqueline; VanderWeele, David; Rettig, Matthew; Heath, Elisabeth I; Quigley, David; Huang, Jiaoti; Chumber, Arun; Cheung, Alexander; Foye, Adam; Leung, Stanley; Abbey, Jill; Dorr, Andrew; Nasoff, Marc; Hunter, John; Wang, Steven; Flavell, Robert R; Fong, Lawrence; Liu, Bin; Small, Eric J

Tumor cell heterogeneity drives spatial organization of the intratumoral immune response.

肿瘤细胞异质性驱动肿瘤内免疫反应的空间组织

Tanaka Miho, Lum Lotus, Hu Kenneth H, Chaudhary Piyush, Hughes Savannah, Ledezma-Soto Cecilia, Samad Bushra, Superville Daphne, Ng Kenneth, Chumber Arun, Benson Ciara, Adams Zoe N, Kersten Kelly, Aguilar Oscar A, Fong Lawrence, Combes Alexis J, Krummel Matthew F, Reeves Melissa Q

Combining therapeutic vaccines with chemo- and immunotherapies in the treatment of cancer

将治疗性疫苗与化疗和免疫疗法相结合用于癌症治疗

Kerr, Matthew D; McBride, David A; Chumber, Arun K; Shah, Nisarg J