Prior antibiotic administration disrupts anti-PD-1 responses in advanced gastric cancer by altering the gut microbiome and systemic immune response
既往抗生素治疗会通过改变肠道菌群和全身免疫反应,干扰晚期胃癌中的抗PD-1反应。
期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2023.101251
Kim, Chang Gon; Koh, June-Young; Shin, Su-Jin; Shin, Ji-Hee; Hong, Moonki; Chung, Hyun Cheol; Rha, Sun Young; Kim, Hyo Song; Lee, Choong-Kun; Lee, Ji Hyun; Han, Yejeong; Kim, Hyoyong; Che, Xiumei; Yun, Un-Jung; Kim, Hyunki; Kim, Jee Hung; Lee, Seo Young; Park, Su Kyoung; Park, Sejung; Kim, Hyunwook; Ahn, Jin Young; Jeung, Hei-Cheul; Lee, Jeong Seok; Nam, Young-Do; Jung, Minkyu
胃癌
肿瘤
肿瘤免疫
微生物学
肠道菌群
PD-1
免疫/内分泌