日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

RGS10 mitigates high glucose-induced microglial inflammation via the reactive oxidative stress pathway and enhances synuclein clearance in microglia

RGS10通过活性氧化应激通路减轻高糖诱导的小胶质细胞炎症,并增强小胶质细胞中突触核蛋白的清除。

Chung, Jaegwon; Jernigan, Janna; Menees, Kelly B; Lee, Jae-Kyung

NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy

NK细胞可清除α-突触核蛋白,而NK细胞的耗竭会加剧α-突触核蛋白病小鼠模型中的突触核蛋白病理。

Earls, Rachael H; Menees, Kelly B; Chung, Jaegwon; Gutekunst, Claire-Anne; Lee, Hyun Joon; Hazim, Manuel G; Rada, Balázs; Wood, Levi B; Lee, Jae-Kyung

Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease

候选炎症生物标志物与α-突触核蛋白表现出独特的关联,并与帕金森病患者的疾病严重程度指标相关。

Eidson, Lori N; Kannarkat, George T; Barnum, Christopher J; Chang, Jianjun; Chung, Jaegwon; Caspell-Garcia, Chelsea; Taylor, Peggy; Mollenhauer, Brit; Schlossmacher, Michael G; Ereshefsky, Larry; Yen, Mark; Kopil, Catherine; Frasier, Mark; Marek, Kenneth; Hertzberg, Vicki S; Tansey, Malú G

Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration

外周和中枢免疫细胞中G蛋白信号调节因子(RGS)-10表达的年龄相关性变化可能影响与年龄相关的退行性变风险。

Kannarkat, George T; Lee, Jae-Kyung; Ramsey, Chenere P; Chung, Jaegwon; Chang, Jianjun; Porter, Isadora; Oliver, Danielle; Shepherd, Kennie; Tansey, Malú G

Peripheral administration of the selective inhibitor of soluble tumor necrosis factor (TNF) XPro®1595 attenuates nigral cell loss and glial activation in 6-OHDA hemiparkinsonian rats.

外周注射选择性可溶性肿瘤坏死因子 (TNF) 抑制剂 XPro®1595 可减轻 6-OHDA 半侧帕金森病大鼠的黑质细胞丢失和神经胶质活化

Barnum Christopher J, Chen Xi, Chung Jaegwon, Chang Jianjun, Williams Martha, Grigoryan Nelly, Tesi Raymond J, Tansey Malú G