日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism

斑马鱼运动神经元中人源TDP-43过表达可通过功能获得机制诱发类似运动神经元病(MND)的表型。

Hogan, Alison L; Kane, Madison; Chiu, Patrick; Richter, Grant; Maurel, Cindy; Wu, Sharlynn; Scherer, Natalie M; Don, Emily K; Lee, Albert; Blair, Ian P; Chung, Roger S; Morsch, Marco

Critical impact of lysine 136 in TDP-43 phase separation, compartmentalization, and aggregation in living vertebrates.

赖氨酸 136 对活脊椎动物中 TDP-43 相分离、区室化和聚集具有关键影响

Maurel Cindy, Scherer Natalie M, Luu Luan, Radford Rowan A, Hogan Alison, Merjane Jessica, Vidal-Itriago Andres, Don Emily K, Chapman Tyler, Cull Stephen, Vourc'h Patrick, Lisowski Leszek, Lee Albert, Chung Roger S, Morsch Marco

Protocol for characterizing biomolecular condensates through live-cell imaging and analysis.

通过活细胞成像和分析表征生物分子凝聚体的方案

Richter Grant, Maurel Cindy, Hogan Alison, Radford Rowan A W, Lee Albert, Chung Roger S, Morsch Marco

Microglia morphophysiological diversity and its implications for the CNS

小胶质细胞形态生理多样性及其对中枢神经系统的影响

Vidal-Itriago, Andrés; Radford, Rowan A W; Aramideh, Jason A; Maurel, Cindy; Scherer, Natalie M; Don, Emily K; Lee, Albert; Chung, Roger S; Graeber, Manuel B; Morsch, Marco

In vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS)

利用双分子荧光互补(BiFC)技术进行体内验证,以研究肌萎缩侧索硬化症(ALS)中的聚集体形成

Don, Emily K; Maschirow, Alina; Radford, Rowan A W; Scherer, Natalie M; Vidal-Itriago, Andrés; Hogan, Alison; Maurel, Cindy; Formella, Isabel; Stoddart, Jack J; Hall, Thomas E; Lee, Albert; Shi, Bingyang; Cole, Nicholas J; Laird, Angela S; Badrock, Andrew P; Chung, Roger S; Morsch, Marco

Isotope metallomics approaches for medical research

同位素金属组学方法在医学研究中的应用

Mahan, Brandon; Chung, Roger S; Pountney, Dean L; Moynier, Frédéric; Turner, Simon

Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos

化学重编程增强斑马鱼胚胎中的同源定向基因组编辑

Aksoy, Yagiz A; Nguyen, David T; Chow, Sharron; Chung, Roger S; Guillemin, Gilles J; Cole, Nicholas J; Hesselson, Daniel

Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo

实时可视化体内单个脊髓运动神经元氧化应激介导的神经退行性变

Formella, Isabel; Svahn, Adam J; Radford, Rowan A W; Don, Emily K; Cole, Nicholas J; Hogan, Alison; Lee, Albert; Chung, Roger S; Morsch, Marco

The impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration

金属硫蛋白-II对小胶质细胞响应肿瘤坏死因子-α (TNFα) 的反应及其对神经元再生的下游效应的影响

Leung, Jacqueline Y K; Bennett, William R; King, Anna E; Chung, Roger S

Extracellular Interactions of Alpha-Synuclein in Multiple System Atrophy

α-突触核蛋白在多系统萎缩症中的细胞外相互作用

Valdinocci, Dario; Radford, Rowan A W; Goulding, Michael; Hayashi, Junna; Chung, Roger S; Pountney, Dean L