日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IFNβ-pSTAT1-IRF1 axis controls colorectal tumor development through induction of immunogenic Ly6C(+)myeloid cells.

IFNβ-pSTAT1-IRF1轴通过诱导免疫原性Ly6C(+)髓系细胞来控制结直肠肿瘤的发展。

Li Yan, Wu Yanmin, Liang Liyan, Yao Xufeng, Pan Yiyang, Zhang Lurong, Wang Yaxin, Zhang Jian, Chow Kwan T, Lu Chunwan

Slc7a5 promotes T cell anti-tumor immunity through sustaining cytotoxic T lymphocyte effector function

Slc7a5通过维持细胞毒性T淋巴细胞的效应功能来促进T细胞抗肿瘤免疫。

Lu, Chunwan; Liang, Liyan; Wu, Yanmin; Yang, Yingcui; Poschel, Dakota; Zhao, Yang; Pei, Lirong; Yu, Miao; Zoccheddu, Martina; Bombin, Sergei; Ding, Han-Fei; Shi, Huidong; Liu, Kebin

Deep and periventricular white matter hyperintensities exhibit differential metabolic profiles in arteriosclerotic cerebral small vessel disease: an untargeted metabolomics study

动脉粥样硬化性脑小血管病中深部和脑室周围白质高信号表现出不同的代谢特征:一项非靶向代谢组学研究

Ye, Shisheng; Feng, Kaiyan; Zeng, Guofang; Cai, Jiaxin; Liang, Lijuan; Chen, Jiaxin; He, Qishan; Mai, Jianhui; Wu, Qiaoling; Chen, Chunwan; Huang, Haifeng; Yuan, Li; Chen, Hai; Li, Yizhong; Li, Hao; Zhang, Xiong

PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis

PD-L1抑制PD-1+Nrp1lo Treg细胞,从而抑制炎症驱动的结直肠肿瘤发生

Dakota B Poschel ,John D Klement ,Alyssa D Merting ,Chunwan Lu ,Yang Zhao ,Dafeng Yang ,Wei Xiao ,Huabin Zhu ,Ponnala Rajeshwari ,Michael Toscano ,Kimya Jones ,Amanda Barrett ,Roni J Bollag ,Padraic G Fallon ,Huidong Shi ,Kebin Liu

Type I Interferon Activates PD-1 Expression through Activation of the STAT1-IRF2 Pathway in Myeloid Cells

型干扰素通过激活髓系细胞中的 STAT1-IRF2 通路激活 PD-1 表达

Liyan Liang, Yingcui Yang, Kaidi Deng, Yanmin Wu, Yan Li, Liya Bai, Yinsong Wang, Chunwan Lu

The Wdr5-H3K4me3 Epigenetic Axis Regulates Pancreatic Tumor Immunogenicity and Immune Suppression

Wdr5-H3K4me3表观遗传轴调控胰腺肿瘤的免疫原性和免疫抑制

Kaidi Deng ,Liyan Liang ,Yingcui Yang ,Yanmin Wu ,Yan Li ,Rongrong Zhang ,Yulin Tian ,Chunwan Lu

Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

肿瘤PD-L1与髓系PD-1结合,抑制I型干扰素,从而削弱细胞毒性T淋巴细胞的募集。

John D Klement ,Priscilla S Redd ,Chunwan Lu ,Alyssa D Merting ,Dakota B Poschel ,Dafeng Yang ,Natasha M Savage ,Gang Zhou ,David H Munn ,Padraic G Fallon ,Kebin Liu

Editorial: The role of one-carbon metabolism in cancer progression, therapy, and resistance

社论:一碳代谢在癌症进展、治疗和耐药性中的作用

Thakur, Abhimanyu; Hu, Xin; Zhao, Erhu; Lu, Chunwan; Liu, Yanqing; Rustagi, Yashika; Zhang, Kui

5-Fluorouracil Suppresses Colon Tumor through Activating the p53-Fas Pathway to Sensitize Myeloid-Derived Suppressor Cells to FasL+ Cytotoxic T Lymphocyte Cytotoxicity

5-氟尿嘧啶通过激活 p53-Fas 通路使髓系抑制细胞对 FasL+ 细胞毒性 T 淋巴细胞的细胞毒性敏感来抑制结肠肿瘤

Yingcui Yang, Mingqing Zhang, Yongdan Zhang, Kebin Liu, Chunwan Lu

G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes

G6PD 作为代谢检查点,调节肿瘤特异性细胞毒性 T 淋巴细胞中的颗粒酶 B 表达

Chunwan Lu, Dafeng Yang, John D Klement, Yolonda L Colson, Nicholas H Oberlies, Cedric J Pearce, Aaron H Colby, Mark W Grinstaff, Han-Fei Ding, Huidong Shi, Kebin Liu