日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Examination of betahistine bioavailability in combination with the monoamine oxidase B inhibitor, selegiline, in humans-a non-randomized, single-sequence, two-period titration, open label single-center phase 1 study (PK-BeST)

在人体中检验倍他司汀与单胺氧化酶 B 抑制剂司来吉兰联合用药的生物利用度——一项非随机、单序列、两周期滴定、开放标签、单中心 1 期研究 (PK-BeST)

Strupp, Michael; Churchill, Grant C; Naumann, Ivonne; Mansmann, Ulrich; Al Tawil, Amani; Golentsova, Anastasia; Goldschagg, Nicolina

Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder

患者成纤维细胞昼夜节律可预测双相情感障碍患者的锂敏感性

Sanghani, Harshmeena R; Jagannath, Aarti; Humberstone, Thomas; Ebrahimjee, Farid; Thomas, Justyn M; Churchill, Grant C; Cipriani, Andrea; Attenburrow, Mary-Jane; Perestenko, Olga V; Cowley, Sally A; Cader, M Zameel; Peirson, Stuart N; Harrison, Paul J; Foster, Russell G; Goodwin, Guy M; Vasudevan, Sridhar R

Defective platelet function in Niemann-Pick disease type C1

尼曼-匹克病C1型血小板功能缺陷

Chen, Oscar C W; Colaco, Alexandria; Davis, Lianne C; Kiskin, Fedir N; Farhat, Nicole Y; Speak, Anneliese O; Smith, David A; Morris, Lauren; Eden, Emily; Tynan, Patricia; Churchill, Grant C; Galione, Antony; Porter, Forbes D; Platt, Frances M

Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts

在GBA1相关帕金森病患者的成纤维细胞中,内质网和溶酶体Ca²⁺储存发生重塑。

Kilpatrick, Bethan S; Magalhaes, Joana; Beavan, Michelle S; McNeill, Alisdair; Gegg, Matthew E; Cleeter, Michael W J; Bloor-Young, Duncan; Churchill, Grant C; Duchen, Michael R; Schapira, Anthony H; Patel, Sandip

Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla

潜在锂模拟物依布硒仑对脑神经化学的影响:7特斯拉磁共振波谱研究

Masaki, Charles; Sharpley, Ann L; Godlewska, Beata R; Berrington, Adam; Hashimoto, Tasuku; Singh, Nisha; Vasudevan, Sridhar R; Emir, Uzay E; Churchill, Grant C; Cowen, Philip J

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing

潜在的锂类似物依布硒仑对冲动性和情绪加工的影响

Masaki, Charles; Sharpley, Ann L; Cooper, Charlotte M; Godlewska, Beata R; Singh, Nisha; Vasudevan, Sridhar R; Harmer, Catherine J; Churchill, Grant C; Sharp, Trevor; Rogers, Robert D; Cowen, Philip J

The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles.

肌醇-3-磷酸合成酶生物合成酶具有独特的催化和代谢作用

Frej Anna D, Clark Jonathan, Le Roy Caroline I, Lilla Sergio, Thomason Peter A, Otto Grant P, Churchill Grant, Insall Robert H, Claus Sandrine P, Hawkins Phillip, Stephens Len, Williams Robin S B

Release of calcium from endolysosomes increases calcium influx through N-type calcium channels: Evidence for acidic store-operated calcium entry in neurons

内溶酶体释放钙离子会增加通过N型钙通道的钙离子内流:神经元中酸性储存操纵性钙离子内流的证据

Hui, Liang; Geiger, Nicholas H; Bloor-Young, Duncan; Churchill, Grant C; Geiger, Jonathan D; Chen, Xuesong

Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart

溶酶体-肌浆网连接处的双孔通道(TPC2)和烟酸腺嘌呤二核苷酸磷酸(NAADP)参与心脏中的急性和慢性β-肾上腺素受体信号传导

Capel, Rebecca A; Bolton, Emma L; Lin, Wee K; Aston, Daniel; Wang, Yanwen; Liu, Wei; Wang, Xin; Burton, Rebecca-Ann B; Bloor-Young, Duncan; Shade, Kai-Ting; Ruas, Margarida; Parrington, John; Churchill, Grant C; Lei, Ming; Galione, Antony; Terrar, Derek A

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells

烟酸腺嘌呤二核苷酸磷酸(NAADP)和内溶酶体双孔通道调节小鼠胰岛β细胞的膜兴奋性和刺激-分泌偶联

Arredouani, Abdelilah; Ruas, Margarida; Collins, Stephan C; Parkesh, Raman; Clough, Frederick; Pillinger, Toby; Coltart, George; Rietdorf, Katja; Royle, Andrew; Johnson, Paul; Braun, Matthias; Zhang, Quan; Sones, William; Shimomura, Kenju; Morgan, Anthony J; Lewis, Alexander M; Chuang, Kai-Ting; Tunn, Ruth; Gadea, Joaquin; Teboul, Lydia; Heister, Paula M; Tynan, Patricia W; Bellomo, Elisa A; Rutter, Guy A; Rorsman, Patrik; Churchill, Grant C; Parrington, John; Galione, Antony