日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GMP-Compliant Process for the Manufacturing of an Extracellular Vesicles-Enriched Secretome Product Derived From Cardiovascular Progenitor Cells Suitable for a Phase I Clinical Trial.

符合 GMP 标准的工艺,用于生产源自心血管祖细胞的富含细胞外囊泡的分泌组产品,适用于 I 期临床试验

Humbert Camille, Cordier Chloé, Drut Iouri, Hamrick Michele, Wong Jacquelyn, Bellamy Valérie, Flaire Justine, Bakshy Kiranmayee, Dingli Florent, Loew Damarys, Larghero Jérôme, Fabreguettes Jean-Roch, Menasché Philippe, Renault Nisa K, Churlaud Guillaume

First-in-man use of a cardiovascular cell-derived secretome in heart failure. Case report

心血管细胞来源分泌组在心力衰竭中的首次人体应用:病例报告

Menasché, Philippe; Renault, Nisa K; Hagège, Albert; Puscas, Tania; Bellamy, Valérie; Humbert, Camille; Le, Laetitia; Blons, Hélène; Granier, Clémence; Benhamouda, Nadine; Bacher, Anne; Churlaud, Guillaume; Sabatier, Brigitte; Larghero, Jérôme

Treatment of COVID-19-associated ARDS with umbilical cord-derived mesenchymal stromal cells in the STROMA-CoV-2 multicenter randomized double-blind trial: long-term safety, respiratory function, and quality of life

在STROMA-CoV-2多中心随机双盲试验中,采用脐带间充质干细胞治疗COVID-19相关ARDS:长期安全性、呼吸功能和生活质量

Sitbon, Alexandre; Hauw-Berlemont, Caroline; Mebarki, Miryam; Heming, Nicholas; Mayaux, Julien; Diehl, Jean-Luc; Demoule, Alexandre; Annane, Djillali; Marois, Clémence; Demeret, Sophie; Weiss, Emmanuel; Voiriot, Guillaume; Fartoukh, Muriel; Constantin, Jean-Michel; Mégarbane, Bruno; Plantefève, Gaëtan; Boucher-Pillet, Hélène; Churlaud, Guillaume; Cras, Audrey; Maheux, Camille; Pezzana, Chloé; Diallo, Mamadou Hassimiou; Lebbah, Said; Ropers, Jacques; Salem, Joe-Elie; Straus, Christian; Menasché, Philippe; Larghero, Jérôme; Monsel, Antoine

Endothelial CD34 expression and regulation of immune cell response in-vitro

内皮细胞CD34表达及其对体外免疫细胞反应的调控

Lousineh Arakelian # ,Julien Lion # ,Guillaume Churlaud ,Rezlene Bargui ,Briac Thierry ,Evelyne Mutabazi ,Patrick Bruneval ,Antonio José Alberdi ,Christelle Doliger ,Maëva Veyssiere ,Jérôme Larghero # ,Nuala Mooney #

Therapeutic potential of extracellular vesicles derived from cardiac progenitor cells in rodent models of chemotherapy-induced cardiomyopathy

源自心脏祖细胞的细胞外囊泡在化疗诱导心肌病啮齿动物模型中的治疗潜力

Desgres, Manon; Lima Correa, Bruna; Petrusca, Lorena; Autret, Gwennhael; Pezzana, Chloé; Marigny, Céline; Guillas, Chloé; Bellamy, Valérie; Vilar, José; Perier, Marie-Cécile; Dingli, Florent; Loew, Damarys; Humbert, Camille; Larghero, Jérôme; Churlaud, Guillaume; Renault, Nisa; Croisille, Pierre; Hagège, Albert; Silvestre, Jean-Sébastien; Menasché, Philippe

Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trial

利用间充质干细胞治疗 COVID-19 相关 ARDS:一项多中心随机双盲试验

Monsel, Antoine; Hauw-Berlemont, Caroline; Mebarki, Miryam; Heming, Nicholas; Mayaux, Julien; Nguekap Tchoumba, Otriv; Diehl, Jean-Luc; Demoule, Alexandre; Annane, Djillali; Marois, Clémence; Demeret, Sophie; Weiss, Emmanuel; Voiriot, Guillaume; Fartoukh, Muriel; Constantin, Jean-Michel; Mégarbane, Bruno; Plantefève, Gaëtan; Malard-Castagnet, Stéphanie; Burrel, Sonia; Rosenzwajg, Michelle; Tchitchek, Nicolas; Boucher-Pillet, Hélène; Churlaud, Guillaume; Cras, Audrey; Maheux, Camille; Pezzana, Chloé; Diallo, Mamadou Hassimiou; Ropers, Jacques; Menasché, Philippe; Larghero, Jérôme

Low-dose IL-2 shapes a tolerogenic gut microbiota that improves autoimmunity and gut inflammation

低剂量 IL-2 可形成耐受性肠道菌群,改善自身免疫和肠道炎症

Nicolas Tchitchek, Otriv Nguekap Tchoumba, Gabriel Pires, Sarah Dandou, Julien Campagne, Guillaume Churlaud, Gwladys Fourcade, Thomas W Hoffmann, Francesco Strozzi, Camille Gaal, Christophe Bonny, Emmanuelle Le Chatelier, Stanislav Dusko Erlich, Harry Sokol, David Klatzmann

Development of a human umbilical cord-derived mesenchymal stromal cell-based advanced therapy medicinal product to treat immune and/or inflammatory diseases

开发基于人脐带间充质基质细胞的先进治疗药物,用于治疗免疫和/或炎症疾病

Miryam Mebarki, Nathan Iglicki, Céline Marigny, Camille Abadie, Claire Nicolet, Guillaume Churlaud, Camille Maheux, Hélène Boucher, Antoine Monsel, Philippe Menasché, Jérôme Larghero, Lionel Faivre, Audrey Cras

Impaired Activated/Memory Regulatory T Cell Clonal Expansion Instigates Diabetes in NOD Mice

活化/记忆调节性 T 细胞克隆扩增受损导致 NOD 小鼠罹患糖尿病

Vanessa Mhanna, Gwladys Fourcade, Pierre Barennes, Valentin Quiniou, Hang P Pham, Paul-Gydeon Ritvo, Faustine Brimaud, Bruno Gouritin, Guillaume Churlaud, Adrien Six, Encarnita Mariotti-Ferrandiz, David Klatzmann

Pre-treatment with IL2 gene therapy alleviates Staphylococcus aureus arthritis in mice

IL2 基因疗法预处理可缓解小鼠金黄色葡萄球菌关节炎

Berglind Bergmann, Ying Fei, Pernilla Jirholt, Zhicheng Hu, Maria Bergquist, Abukar Ali, Catharina Lindholm, Olov Ekwall, Guillaume Churlaud, David Klatzmann, Tao Jin, Inger Gjertsson