日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deletion of the WD40 domain of ATG16L1 exacerbates acute pancreatitis, abolishes LAP-like non-canonical autophagy and slows trypsin degradation

ATG16L1 的 WD40 结构域缺失会加重急性胰腺炎,消除 LAP 样非经典自噬并减缓胰蛋白酶降解

Michael Chvanov, Svetlana Voronina, Matthew Jefferson, Ulrike Mayer, Robert Sutton, David N Criddle, Thomas Wileman, Alexei V Tepikin

Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle

自噬、急性胰腺炎和胰蛋白酶原激活细胞器的变态

Voronina, Svetlana; Chvanov, Michael; De Faveri, Francesca; Mayer, Ulrike; Wileman, Tom; Criddle, David; Tepikin, Alexei

Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1

坏死抑制素-1 在急性胰腺炎中的保护作用:受体相互作用蛋白激酶 1 的部分参与

Yulin Ouyang, Li Wen, Jane A Armstrong, Michael Chvanov, Diane Latawiec, Wenhao Cai, Mohammad Awais, Rajarshi Mukherjee, Wei Huang, Peter J Gough, John Bertin, Alexei V Tepikin, Robert Sutton, David N Criddle

LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells

胰腺腺泡细胞中 LAP 样非典型自噬和内吞空泡的进化

Francesca De Faveri, Michael Chvanov, Svetlana Voronina, Danielle Moore, Liam Pollock, Lee Haynes, Muhammad Awais, Alison J Beckett, Ulrike Mayer, Robert Sutton, David N Criddle, Ian A Prior, Tom Wileman, Alexei V Tepikin

Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does Not Reduce Severity of Experimental Acute Pancreatitis

线粒体钙单向转运体的敲除强烈抑制胰腺腺泡细胞中的刺激-代谢偶联,但不会降低实验性急性胰腺炎的严重程度

Michael Chvanov, Svetlana Voronina, Xiaoying Zhang, Svetlana Telnova, Robert Chard, Yulin Ouyang, Jane Armstrong, Helen Tanton, Muhammad Awais, Diane Latawiec, Robert Sutton, David N Criddle, Alexei V Tepikin

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

碱性氨基酸诱发胰腺损伤的机制在 L-精氨酸、L-鸟氨酸和 L-组氨酸之间有所不同

Xiaoying Zhang, Tao Jin, Na Shi, Linbo Yao, Xinmin Yang, Chenxia Han, Li Wen, Dan Du, Peter Szatmary, Rajarshi Mukherjee, Tingting Liu, Qing Xia, David N Criddle, Wei Huang, Michael Chvanov, Robert Sutton

Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis

胰腺腺泡细胞内吞泡的细胞内破裂、胞吐作用和肌动蛋白相互作用:急性胰腺炎的起始事件

Chvanov, Michael; De Faveri, Francesca; Moore, Danielle; Sherwood, Mark W; Awais, Muhammad; Voronina, Svetlana; Sutton, Robert; Criddle, David N; Haynes, Lee; Tepikin, Alexei V

TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death

TRO40303 通过减少脂肪酸乙酯诱导的线粒体损伤和坏死性细胞死亡改善酒精诱发的胰腺炎

Muhammad Ahsan Javed, Li Wen, Muhammad Awais, Diane Latawiec, Wei Huang, Michael Chvanov, Sophie Schaller, Thierry Bordet, Magali Michaud, Rebecca Pruss, Alexei Tepikin, David Criddle, Robert Sutton

Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release

咖啡因通过抑制肌醇1,4,5-三磷酸受体介导的Ca2+释放来预防实验性急性胰腺炎。

Huang, Wei; Cane, Matthew C; Mukherjee, Rajarshi; Szatmary, Peter; Zhang, Xiaoying; Elliott, Victoria; Ouyang, Yulin; Chvanov, Michael; Latawiec, Diane; Wen, Li; Booth, David M; Haynes, Andrea C; Petersen, Ole H; Tepikin, Alexei V; Criddle, David N; Sutton, Robert

The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells

Ca2+内流在胰腺腺泡细胞内吞空泡形成中的作用

Voronina, Svetlana; Collier, David; Chvanov, Michael; Middlehurst, Ben; Beckett, Alison J; Prior, Ian A; Criddle, David N; Begg, Malcolm; Mikoshiba, Katsuhiko; Sutton, Robert; Tepikin, Alexei V