日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson's Disease

WDR44驱动溶酶体膜上新生α-突触核蛋白的聚集,并促进帕金森病中的神经元功能障碍。

Teixeira, Maxime; Sheta, Razan; Bérard, Morgan; Insinna, Christine; Mahul-Mellier, Anne-Laure; Delmas, Constantin V L; Lépinay, Eva; Idi, Walid; Ricard, Alexandra; Cid-Pellitero, Esther Del; Trabolsi, Christine; Gobeil, Stéphane; Canron, Marie-Hélène; Bézard, Erwan; Rajput, Alex; Cicchetti, Francesca; Parent, Martin; Fon, Edward A; Ramalingam, Nagendran; Dettmer, Ulf; Calon, Frederic; Westlake, Christopher; Lashuel, Hilal A; Oueslati, Abid

Restoring brain barriers: an innovative approach for treating neurological disorders

修复脑屏障:治疗神经系统疾病的创新方法

Lemarchant, Sighild; Engelhardt, Britta; Cicchetti, Francesca; Bix, Gregory J; Janus, Annette; Godfrin, Yann; Blasco, Hélène; Campbell, Matthew; de Rus Jacquet, Aurélie

Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration.

红细胞衍生的细胞外囊泡通过血脑屏障进行胞吞作用,诱发类似帕金森病的神经退行性变

Denis Hélèna L, de Rus Jacquet Aurélie, Alpaugh Melanie, Panisset Michel, Barker Roger A, Boilard Éric, Cicchetti Francesca

Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.

从亨廷顿病患者体内分离出的血小板中的 Tau 蛋白水平可作为疾病严重程度的生物标志物

Alpaugh Melanie, Lantero-Rodriguez Juan, Benedet Andrea L, Manseau Uriel, Boutin Martine, Maiuri Massimo, Denis Helena L, Masnata Maria, Fazal Shaline V, Chouinard Sylvain, Rosa-Neto Pedro, Barker Roger A, Blennow Kaj, Zetterberg Henrik, Labib Richard, Cicchetti Francesca

Parkinson's Disease-vulnerable and -resilient dopamine neurons display opposite responses to excitatory input.

易患帕金森病和不易患帕金森病的多巴胺神经元对兴奋性输入表现出相反的反应

Hadjas Lotfi C, Kollman Grace J, Linderhof Lexe, Xia Mingxuan, Mansur Syon, Saint-Pierre Martine, Lim Byung Kook, Lee Edward B, Cicchetti Francesca, Awatramani Rajeshwar, Hollon Nick G, Hnasko Thomas S

Evidence of mutant huntingtin and tau-related pathology within neuronal grafts in Huntington's disease cases

亨廷顿病病例中神经元移植组织内存在突变亨廷顿蛋白和tau蛋白相关病理的证据

Salem, Shireen; Kilgore, Mitchell D; Anwer, Mehwish; Maxan, Alexander; Child, Dan; Bird, Thomas D; Keene, C Dirk; Cicchetti, Francesca; Latimer, Caitlin

Prompting endogenous repair of brain injury: science fiction or reality?

促进脑损伤的内源性修复:科幻还是现实?

de Rus Jacquet, Aurelie; Cicchetti, Francesca

Correction: Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology

更正:揭示亨廷顿舞蹈症的新视角:血液如何既能传播又能缓解疾病病理

Rieux, Marie; Alpaugh, Melanie; Sciacca, Giacomo; Saint-Pierre, Martine; Masnata, Maria; Denis, Hélèna L; Lévesque, Sébastien A; Herrmann, Frank; Bazenet, Chantal; Garneau, Alexandre P; Isenring, Paul; Truant, Ray; Oueslati, Abid; Gould, Peter V; Ast, Anne; Wanker, Erich E; Lacroix, Steve; Cicchetti, Francesca

Correction to: Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders

更正:诱导多能干细胞模型在研究神经退行性疾病中的病理蛋白方面的当前和未来应用

de Rus Jacquet, Aurélie; Denis, Hélèna L; Cicchetti, Francesca; Alpaugh, Melanie

Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders

诱导多能干细胞模型在神经退行性疾病病理蛋白研究中的当前及未来应用

de Rus Jacquet, Aurélie; Denis, Hélèna L; Cicchetti, Francesca; Alpaugh, Melanie