日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male Mice

雄性小鼠体内四氯乙烯毒代动力学组织和代谢物特异性群体变异性的定量表征

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfab057
Dalaijamts, Chimeddulam; Cichocki, Joseph A; Luo, Yu-Syuan; Rusyn, Ivan; Chiu, Weihsueh A
代谢
发表日期：2021
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PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in mice

利用生理药代动力学模型研究非酒精性脂肪肝疾病对小鼠体内四氯乙烯毒代动力学的影响

期刊:Toxicology and Applied Pharmacology
影响因子:3.4
doi:10.1016/j.taap.2020.115069
Dalaijamts, Chimeddulam; Cichocki, Joseph A; Luo, Yu-Syuan; Rusyn, Ivan; Chiu, Weihsueh A
脂肪肝
代谢
发表日期：2020
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Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene.

利用合作交叉小鼠群体填补风险评估中的数据空白：以四氯乙烯的毒代动力学和肾脏毒效动力学群体分析为例

期刊:Environmental Health Perspectives
影响因子:9.8
doi:10.1289/EHP5105
Luo Yu-Syuan, Cichocki Joseph A, Hsieh Nan-Hung, Lewis Lauren, Wright Fred A, Threadgill David W, Chiu Weihsueh A, Rusyn Ivan
其它
Mouse
发表日期：2019
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Incorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in mice

将谷胱甘肽结合途径纳入小鼠体内四氯乙烯的更新生理药代动力学模型中

期刊:Toxicology and Applied Pharmacology
影响因子:3.4
doi:10.1016/j.taap.2018.05.033
Dalaijamts, Chimeddulam; Cichocki, Joseph A; Luo, Yu-Syuan; Rusyn, Ivan; Chiu, Weihsueh A
发表日期：2018
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Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population

利用合作杂交小鼠群体对四氯乙烯毒物动力学和毒物效应动力学的变异性进行表征

期刊:Environmental Health Perspectives
影响因子:9.8
doi:10.1289/EHP788
Cichocki, Joseph A; Furuya, Shinji; Venkatratnam, Abhishek; McDonald, Thomas J; Knap, Anthony H; Wade, Terry; Sweet, Stephen; Chiu, Weihsueh A; Threadgill, David W; Rusyn, Ivan
Mouse
发表日期：2017
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Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse

编辑推荐：三氯乙烯和四氯乙烯对B6C3F1小鼠肝肾转录组影响的剂量反应比较分析

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfx165
Zhou, Yi-Hui; Cichocki, Joseph A; Soldatow, Valerie Y; Scholl, Elizabeth H; Gallins, Paul J; Jima, Dereje; Yoo, Hong-Sik; Chiu, Weihsueh A; Wright, Fred A; Rusyn, Ivan
Mouse
发表日期：2017
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Simultaneous detection of the tetrachloroethylene metabolites S-(1,2,2-trichlorovinyl) glutathione, S-(1,2,2-trichlorovinyl)-L-cysteine, and N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine in multiple mouse tissues via ultra-high performance liquid chromatography electrospray ionization tandem mass spectrometry

利用超高效液相色谱-电喷雾电离串联质谱法同时检测多种小鼠组织中的四氯乙烯代谢物S-(1,2,2-三氯乙烯基)谷胱甘肽、S-(1,2,2-三氯乙烯基)-L-半胱氨酸和N-乙酰基-S-(1,2,2-三氯乙烯基)-L-半胱氨酸

期刊:
影响因子:
doi:10.1080/15287394.2017.1330585
Luo, Yu-Syuan; Cichocki, Joseph A; McDonald, Thomas J; Rusyn, Ivan
代谢
发表日期：2017
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Target Organ Metabolism, Toxicity, and Mechanisms of Trichloroethylene and Perchloroethylene: Key Similarities, Differences, and Data Gaps

三氯乙烯和四氯乙烯的靶器官代谢、毒性和机制：主要异同点和数据缺口

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1124/jpet.116.232629
Cichocki, Joseph A; Guyton, Kathryn Z; Guha, Neela; Chiu, Weihsueh A; Rusyn, Ivan; Lash, Lawrence H
毒理研究
代谢
发表日期：2016
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The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.

过氧化物酶体增殖激活受体α对三氯乙烯毒物动力学和毒物效应之间关系的影响

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfv134
Yoo Hong Sik, Cichocki Joseph A, Kim Sungkyoon, Venkatratnam Abhishek, Iwata Yasuhiro, Kosyk Oksana, Bodnar Wanda, Sweet Stephen, Knap Anthony, Wade Terry, Campbell Jerry, Clewell Harvey J, Melnyk Stepan B, Chiu Weihsueh A, Rusyn Ivan
免疫/内分泌
发表日期：2015
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