Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite-binding site
天然(二氢)菲类植物化合物通过其变构药物和代谢物结合位点直接激活AMPK。
期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2022.101852
Matthew J Sanders ,Yann Ratinaud ,Katyayanee Neopane ,Nicolas Bonhoure ,Emily A Day ,Olivier Ciclet ,Steve Lassueur ,Martine Naranjo Pinta ,Maria Deak ,Benjamin Brinon ,Stefan Christen ,Gregory R Steinberg ,Denis Barron ,Kei Sakamoto