Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice
Igf2衍生的Mir483过度表达会抑制Igf1表达,并导致小鼠发育生长受限和代谢功能障碍。
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2024.114750
Ionel Sandovici,Denise S Fernandez-Twinn,Niamh Campbell,Wendy N Cooper,Yoichi Sekita,Ilona Zvetkova,David Ferland-McCollough,Haydn M Prosser,Lila M Oyama,Lucas C Pantaleão,Danilo Cimadomo,Karina Barbosa de Queiroz,Cecilia S K Cheuk,Nicola M Smith,Richard G Kay,Robin Antrobus,Katharina Hoelle,Marcella K L Ma,Noel H Smith,Stefan H Geyer,Lukas F Reissig,Wolfgang J Weninger,Kenneth Siddle,Anne E Willis,Brian Y H Lam,Martin Bushell,Susan E Ozanne,Miguel Constância