日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson's disease revealed by in vivo PET imaging.

体内PET成像显示，LRRK2-R1441C大鼠早期帕金森病模型背侧纹状体中多巴胺D2受体上调

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-99580-x
Delgado-Goñi Teresa, Connor-Robson Natalie, Cioroch Milena, Paisey Stephen, Marshall Christopher, Lane Emma L, Hauton David, McCullagh James, Magill Peter J, Cragg Stephanie J, Mackay Clare E, Wade-Martins Richard, Klein Johannes C
神经科学
Rat
发表日期：2025
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REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model

在α-突触核蛋白过表达的BAC转基因小鼠模型中，REST可保护多巴胺能神经元免受线粒体和α-突触核蛋白寡聚体病理的影响

期刊:Journal of Neuroscience
影响因子:4.4
doi:10.1523/JNEUROSCI.1478-20.2021
Brent J Ryan ，Nora Bengoa-Vergniory ，Matthew Williamson ，Ecem Kirkiz ，Rosalind Roberts ，Gabriele Corda ，Maximilian Sloan ，Saba Saqlain ，Marta Cherubini ，Josse Poppinga ，Helle Bogtofte ，Milena Cioroch ，Svenja Hester ，Richard Wade-Martins
神经科学
Mouse
REST
线粒体
发表日期：2021
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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease

CLR01 在体外和帕金森病小鼠模型中保护多巴胺能神经元

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-020-18689-x
Nora Bengoa-Vergniory, Emilie Faggiani, Paula Ramos-Gonzalez, Ecem Kirkiz, Natalie Connor-Robson, Liam V Brown, Ibrar Siddique, Zizheng Li, Siv Vingill, Milena Cioroch, Fabio Cavaliere, Sarah Threlfell, Bradley Roberts, Thomas Schrader, Frank-Gerrit Klärner, Stephanie Cragg, Benjamin Dehay, Gal Bita
神经
帕金森
ELISA
Mouse
发表日期：2020
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Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior

多巴胺神经元巨自噬受损对帕金森病病理和行为有相反的影响

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2019.09.029
Benjamin H M Hunn, Siv Vingill, Sarah Threlfell, Javier Alegre-Abarrategui, Morgane Magdelyns, Thierry Deltheil, Nora Bengoa-Vergniory, Peter L Oliver, Milena Cioroch, Natalie M Doig, David M Bannerman, Stephanie J Cragg, Richard Wade-Martins
信号转导
神经
帕金森
Autophagy
Donkey
IgG
发表日期：2019
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A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor

基因组 DNA 报告筛选鉴定出与他汀类药物协同作用以上调低密度脂蛋白受体的角鲨烯合酶抑制剂

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.1
doi:10.1124/jpet.116.239574
Alastair G Kerr, Lawrence C S Tam, Ashley B Hale, Milena Cioroch, Gillian Douglas, Sarina Agkatsev, Olivia Hibbitt, Joseph Mason, James Holt-Martyn, Carole J R Bataille, Graham M Wynne, Keith M Channon, Angela J Russell, Richard Wade-Martins
信号转导
发表日期：2017
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Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles

基于病毒样颗粒的寡聚 α-突触核蛋白疫苗的临床前开发

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0181844
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H M Hunn, Nora Bengoa-Vergniory, Milena Cioroch, Mauricio Ramm, Amy M Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F Bachmann
免疫
微生物学
发表日期：2017
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Pcsk5 is required in the early cranio-cardiac mesoderm for heart development

PCSK5在早期颅心中胚层中对心脏发育是必需的

期刊:BMC Developmental Biology
影响因子:
doi:10.1186/s12861-017-0148-y
Szumska, Dorota; Cioroch, Milena; Keeling, Angela; Prat, Annik; Seidah, Nabil G; Bhattacharya, Shoumo
发育与干细胞
CSK
发表日期：2017
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Episomal Nonviral Gene Therapy Vectors Slow Progression of Atherosclerosis in a Model of Familial Hypercholesterolemia

染色体外非病毒基因治疗载体减缓家族性高胆固醇血症模型中动脉粥样硬化的进展

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.5
doi:10.1038/mtna.2016.86
Alastair G Kerr, Lawrence Cs Tam, Ashley B Hale, Milena Cioroch, Gillian Douglas, Keith M Channon, Richard Wade-Martins
微生物学
心血管
动脉粥样硬化
发表日期：2016
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LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function

LRRK2 BAC 转基因大鼠出现进行性 L-DOPA 反应性运动障碍，以及多巴胺回路功能缺陷

期刊:Human Molecular Genetics
影响因子:3.1
doi:10.1093/hmg/ddv628
Max Sloan, Javier Alegre-Abarrategui, Dawid Potgieter, Anna-Kristin Kaufmann, Richard Exley, Thierry Deltheil, Sarah Threlfell, Natalie Connor-Robson, Katherine Brimblecombe, Rebecca Wallings, Milena Cioroch, David M Bannerman, J Paul Bolam, Peter J Magill, Stephanie J Cragg, Paul D Dodson, Richard
信号转导
Donkey
IgG
发表日期：2016
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Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse

新型 A30P α-突触核蛋白 BAC 转基因小鼠存在区域特异性多巴胺信号传导缺陷，但去甲肾上腺素信号传导没有缺陷

期刊:Neurobiology of Disease
影响因子:5.1
doi:10.1016/j.nbd.2013.10.005
Tonya N Taylor, Dawid Potgieter, Sabina Anwar, Steven L Senior, Stephanie Janezic, Sarah Threlfell, Brent Ryan, Laura Parkkinen, Thierry Deltheil, Milena Cioroch, Achilleas Livieratos, Peter L Oliver, Katie A Jennings, Kay E Davies, Olaf Ansorge, David M Bannerman, Stephanie J Cragg, Richard Wade-Ma
信号转导
Mouse
发表日期：2014
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