日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Six Drivers of Aging Identified Among Genes Differentially Expressed With Age

在随年龄差异表达的基因中,已确定六个衰老驱动因素

Coler-Reilly, Ariella; Pincus, Zachary; Scheller, Erica L; Civitelli, Roberto

N-cadherin in osteolineage cells restrains breast cancer cell growth via inhibition of a PI3K-dependent, Tgf-β1-driven feed-forward loop

骨谱细胞中的N-钙黏蛋白通过抑制PI3K依赖性、TGF-β1驱动的前馈环路来抑制乳腺癌细胞的生长。

Sugatani, Toshifumi; Yeo, Kate; Campioli, Marco; Fujimoto, Hillary; Civitelli, Roberto

Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength

2型糖尿病患者骨骼中经典Wnt信号通路表达下调,且与晚期糖基化终产物(AGEs)含量升高和骨强度降低相关。

Leanza, Giulia; Cannata, Francesca; Faraj, Malak; Pedone, Claudio; Viola, Viola; Tramontana, Flavia; Pellegrini, Niccolò; Vadalà, Gianluca; Piccoli, Alessandra; Strollo, Rocky; Zalfa, Francesca; Beeve, Alec T; Scheller, Erica L; Tang, Simon Y; Civitelli, Roberto; Maccarrone, Mauro; Papalia, Rocco; Napoli, Nicola

Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice

间充质谱系细胞中的连接蛋白43调节小鼠的体脂含量和能量代谢。

Lee, Seung-Yon; Fontana, Francesca; Sugatani, Toshifumi; Portales Castillo, Ignacio; Leanza, Giulia; Coler-Reilly, Ariella; Civitelli, Roberto

Reduced guanidinoacetate in plasma of patients with autosomal dominant Fanconi syndrome due to heterozygous P341L GATM variant and study of organoids towards treatment.

由于杂合子 P341L GATM 变异导致常染色体显性范可尼综合征患者血浆中胍基乙酸减少,以及类器官治疗的研究

Portales-Castillo Ignacio, Singal Rhea, Ambrose Anastasia, Song Jong Hee, Son Minsoo, Goo Young Ah, Zhou Wen, Traum Avram Z, Coler-Reilly Ariella, Humphreys Benjamin D, Civitelli Roberto, Jüppner Harald, Lundquist Andrew L, Seres Peter, Allegretti Andrew S, Mercimek-Andrews Saadet

Six drivers of aging identified among genes differentially expressed with age

在随年龄差异表达的基因中,已确定了六个衰老驱动因素

Coler-Reilly, Ariella; Pincus, Zachary; Scheller, Erica L; Civitelli, Roberto

Sex- and race-specific associations of bone mineral density with incident heart failure and its subtypes in older adults

老年人骨矿物质密度与新发心力衰竭及其亚型之间的性别和种族特异性关联

Gao, Hans; Patel, Sheena; Fohtung, Raymond B; Cawthon, Peggy M; Newman, Anne B; Cauley, Jane A; Carbone, Laura; Chaves, Paulo H M; Stein, Phyllis K; Civitelli, Roberto; Kizer, Jorge R

Loading-induced bone formation is mediated by Wnt1 induction in osteoblast-lineage cells

负重诱导的骨形成是由成骨细胞谱系细胞中 Wnt1 的诱导介导的。

Lawson, Lisa Y; Migotsky, Nicole; Chermside-Scabbo, Christopher J; Shuster, John T; Joeng, Kyu Sang; Civitelli, Roberto; Lee, Brendan; Silva, Matthew J

Romosozumab improves lumbar spine bone mass and bone strength parameters relative to alendronate in postmenopausal women: results from the Active-Controlled Fracture Study in Postmenopausal Women With Osteoporosis at High Risk (ARCH) trial

与阿仑膦酸钠相比,罗莫索单抗可改善绝经后妇女的腰椎骨量和骨强度参数:来自高危骨质疏松症绝经后妇女主动对照骨折研究(ARCH)试验的结果

Brown, Jacques P; Engelke, Klaus; Keaveny, Tony M; Chines, Arkadi; Chapurlat, Roland; Foldes, A Joseph; Nogues, Xavier; Civitelli, Roberto; De Villiers, Tobias; Massari, Fabio; Zerbini, Cristiano A F; Wang, Zhenxun; Oates, Mary K; Recknor, Christopher; Libanati, Cesar

N-cadherin in osteolineage cells modulates stromal support of tumor growth

骨谱细胞中的N-钙黏蛋白调节基质对肿瘤生长的支持作用

Fontana, Francesca; Xiang, Jingyu; Su, Xinming; Tycksen, Eric; Nassau, Rachel; Fox, Gregory; Leanza, Giulia; Weilbaecher, Katherine; Civitelli, Roberto