日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

器官特异性代谢途径可区分糖尿病前期、 2 型糖尿病和正常组织

Klev Diamanti, Marco Cavalli, Maria J Pereira, Gang Pan, Casimiro Castillejo-López, Chanchal Kumar, Filip Mundt, Jan Komorowski, Atul S Deshmukh, Matthias Mann, Olle Korsgren, Jan W Eriksson, Claes Wadelius

Multifaceted regulation of hepatic lipid metabolism by YY1

YY1对肝脏脂质代谢的多方面调节

Gang Pan, Klev Diamanti, Marco Cavalli, Ariadna Lara Gutiérrez, Jan Komorowski, Claes Wadelius

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

PATZ1 通过与 rs174557 结合来下调 FADS1,并受到 SP1/SREBP1c 的抑制

Gang Pan, Adam Ameur, Stefan Enroth, Madhusudhan Bysani, Helena Nord, Marco Cavalli, Magnus Essand, Ulf Gyllensten, Claes Wadelius

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

等位基因特异性转录因子与与疾病和基因表达相关的常见和罕见变异结合

Marco Cavalli, Gang Pan, Helena Nord, Ola Wallerman, Emelie Wallén Arzt, Olof Berggren, Ingegerd Elvers, Maija-Leena Eloranta, Lars Rönnblom, Kerstin Lindblad Toh, Claes Wadelius

lobChIP: from cells to sequencing ready ChIP libraries in a single day

lobChIP:一天之内从细胞到可测序的 ChIP 文库

Ola Wallerman, Helena Nord, Madhusudhan Bysani, Lisa Borghini, Claes Wadelius

ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

脂肪性肝炎和正常肝组织中的 ChIP-seq 可识别与癌症进展相关的候选疾病机制

Madhusudhan Bysani, Ola Wallerman, Susanne Bornelöv, Kurt Zatloukal, Jan Komorowski, Claes Wadelius

Integrative epigenomic and genomic analysis of malignant pheochromocytoma

恶性嗜铬细胞瘤的综合表观基因组学和基因组学分析

Johanna Sandgren, Robin Andersson, Alvaro Rada-Iglesias, Stefan Enroth, Goran Akerstrom, Jan P Dumanski, Jan Komorowski, Gunnar Westin, Claes Wadelius

Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

通过 ChIP 测序鉴定出 HNF4a、FOXA2 和 GABP 在调控 DNA 元件上的分子相互作用

Ola Wallerman, Mehdi Motallebipour, Stefan Enroth, Kalicharan Patra, Madhu Sudhan Reddy Bysani, Jan Komorowski, Claes Wadelius

Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

ChIP-seq 揭示 HepG2 细胞中 FOXA1 和 FOXA3 的差异结合和共结合模式及其与 H3K4me3 的关系

Mehdi Motallebipour, Adam Ameur, Madhu Sudhan Reddy Bysani, Kalicharan Patra, Ola Wallerman, Jonathan Mangion, Melissa A Barker, Kevin J McKernan, Jan Komorowski, Claes Wadelius

Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

丁酸介导以转录起始位点为中心的组蛋白乙酰化降低和相关基因的下调

Alvaro Rada-Iglesias, Stefan Enroth, Adam Ameur, Christoph M Koch, Gayle K Clelland, Patricia Respuela-Alonso, Sarah Wilcox, Oliver M Dovey, Peter D Ellis, Cordelia F Langford, Ian Dunham, Jan Komorowski, Claes Wadelius