日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials

在接受调节剂治疗的囊性纤维化患者中,停用高渗盐水或重组人脱氧核糖核酸酶(dornase alfa)与继续使用高渗盐水或dornase alfa的疗效比较(SIMPLIFY):两项平行、多中心、开放标签、随机、对照、非劣效性试验的结果

Mayer-Hamblett, Nicole; Ratjen, Felix; Russell, Renee; Donaldson, Scott H; Riekert, Kristin A; Sawicki, Gregory S; Odem-Davis, Katherine; Young, Julia K; Rosenbluth, Daniel; Taylor-Cousar, Jennifer L; Goss, Christopher H; Retsch-Bogart, George; Clancy, John Paul; Genatossio, Alan; O'Sullivan, Brian P; Berlinski, Ariel; Millard, Susan L; Omlor, Gregory; Wyatt, Colby A; Moffett, Kathryn; Nichols, David P; Gifford, Alex H

Advancing the pipeline of cystic fibrosis clinical trials: a new roadmap with a global trial network perspective

推进囊性纤维化临床试验项目:基于全球试验网络视角的新路线图

Mayer-Hamblett, Nicole; Clancy, John Paul; Jain, Raksha; Donaldson, Scott H; Fajac, Isabelle; Goss, Christopher H; Polineni, Deepika; Ratjen, Felix; Quon, Bradley S; Zemanick, Edith T; Bell, Scott C; Davies, Jane C; Jain, Manu; Konstan, Michael W; Kerper, Natanya R; LaRosa, Tré; Mall, Marcus A; McKone, Edward; Pearson, Kelsie; Pilewski, Joseph M; Quittell, Lynne; Rayment, Jonathan H; Rowe, Steven M; Taylor-Cousar, Jennifer L; Retsch-Bogart, George; Downey, Damian G

Understanding and addressing the needs of people with cystic fibrosis in the era of CFTR modulator therapy

在CFTR调节剂疗法时代,了解并满足囊性纤维化患者的需求至关重要。

Hisert, Katherine B; Birket, Susan E; Clancy, John Paul; Downey, Damian G; Engelhardt, John F; Fajac, Isabelle; Gray, Robert D; Lachowicz-Scroggins, Marrah E; Mayer-Hamblett, Nicole; Thibodeau, Patrick; Tuggle, Katherine L; Wainwright, Claire E; De Boeck, Kris

Long-term amikacin liposome inhalation suspension in cystic fibrosis patients with chronic P. aeruginosa infection

囊性纤维化合并慢性铜绿假单胞菌感染患者长期吸入阿米卡星脂质体混悬液的疗效

Bilton, Diana; Fajac, Isabelle; Pressler, Tacjana; Clancy, John Paul; Sands, Dorota; Minic, Predrag; Cipolli, Marco; Galeva, Ivanka; Solé, Amparo; Quittner, Alexandra L; Jumadilova, Zhanna; Ciesielska, Monika; Konstan, Michael W

The impact of SARS-CoV-2 on the cystic fibrosis foundation therapeutics development network

SARS-CoV-2 对囊性纤维化基金会治疗研发网络的影响

Pearson, Kelsie; Mayer-Hamblett, Nicole; Goss, Christopher H; Retsch-Bogart, George Z; VanDalfsen, Jill M; Burks, Patricia; Rosenbluth, Daniel; Clancy, John Paul; Hoffman, Amy; Nichols, David P

Amikacin liposome inhalation suspension for chronic Pseudomonas aeruginosa infection in cystic fibrosis

阿米卡星脂质体吸入混悬液用于治疗囊性纤维化患者的慢性铜绿假单胞菌感染

Bilton, Diana; Pressler, Tacjana; Fajac, Isabelle; Clancy, John Paul; Sands, Dorota; Minic, Predrag; Cipolli, Marco; Galeva, Ivanka; Solé, Amparo; Quittner, Alexandra L; Liu, Keith; McGinnis, John P 2nd; Eagle, Gina; Gupta, Renu; Konstan, Michael W

Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia.

中性粒细胞胞外陷阱激活人支气管上皮细胞中IL-8和IL-1的表达

Hudock Kristin M, Collins Margaret S, Imbrogno Michelle, Snowball John, Kramer Elizabeth L, Brewington John J, Gollomp Kandace, McCarthy Cormac, Ostmann Alicia J, Kopras Elizabeth J, Davidson Cynthia R, Srdiharan Anusha, Arumugam Paritha, Sengupta Shaon, Xu Yan, Worthen G Scott, Trapnell Bruce C, Clancy John Paul

CFTR modulator theratyping: Current status, gaps and future directions

CFTR调节因子治疗分型:现状、差距和未来方向

Clancy, John Paul; Cotton, Calvin U; Donaldson, Scott H; Solomon, George M; VanDevanter, Donald R; Boyle, Michael P; Gentzsch, Martina; Nick, Jerry A; Illek, Beate; Wallenburg, John C; Sorscher, Eric J; Amaral, Margarida D; Beekman, Jeffrey M; Naren, Anjaparavanda P; Bridges, Robert J; Thomas, Philip J; Cutting, Garry; Rowe, Steven; Durmowicz, Anthony G; Mense, Martin; Boeck, Kris D; Skach, William; Penland, Christopher; Joseloff, Elizabeth; Bihler, Hermann; Mahoney, John; Borowitz, Drucy; Tuggle, Katherine L

Sweat chloride as a biomarker of CFTR activity: proof of concept and ivacaftor clinical trial data

汗液氯化物作为CFTR活性生物标志物:概念验证和ivacaftor临床试验数据

Accurso, Frank J; Van Goor, Fredrick; Zha, Jiuhong; Stone, Anne J; Dong, Qunming; Ordonez, Claudia L; Rowe, Steven M; Clancy, John Paul; Konstan, Michael W; Hoch, Heather E; Heltshe, Sonya L; Ramsey, Bonnie W; Campbell, Preston W; Ashlock, Melissa A

Nasal potential difference measurements to assess CFTR ion channel activity

鼻腔电位差测量用于评估CFTR离子通道活性

Rowe, Steven M; Clancy, John Paul; Wilschanski, Michael