日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Autistic behavior is a common outcome of biallelic disruption of PDZD8 in humans and mice

自闭症行为是人类和小鼠中PDZD8双等位基因破坏的常见结果。

Pantiru, Andreea D; Van de Sompele, Stijn; Ligneul, Clemence; Chatelain, Camille; Barrea, Christophe; Lerch, Jason P; Filippi, Beatrice M; Alkan, Serpil; De Baere, Elfride; Johnston, Jamie; Clapcote, Steven J

Alternating Hemiplegia of Childhood and ATP1A3-Related Diseases: Insights From a Decade of Discovery and Collaboration

儿童交替性偏瘫和ATP1A3相关疾病:十年发现与合作的启示

Simpson, Alexander J; McLellan, Ailsa; Behl, Katherine Elizabeth; Brown, Jo; Clapcote, Steven J; Cross, J Helen; van den Maagdenberg, Arn M J M; Vezyroglou, Aikaterini None; Balestrini, Simona; Sisodiya, Sanjay M

In memory of Professor Iain Wilkinson: cognitive and neuroimaging endophenotypes in a consanguineous schizophrenia multiplex family

谨以此文纪念伊恩·威尔金森教授:近亲婚配多重精神分裂症家族的认知和神经影像学内表型

Wilkinson, Iain D; Mahmood, Tariq; Yasmin, Sophia Faye; Tomlinson, Anneka; Nazari, Jamshid; Alhaj, Hamid; El Din, Soumaya Nasser; Neill, Joanna; Pandit, Chhaya; Ashraf, Shahzad; Cardno, Alastair G; Clapcote, Steven J; Inglehearn, Chris F; Woodruff, Peter W

PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies

PDZD8基因缺失会导致人类、小鼠和果蝇的认知障碍

Al-Amri, Ahmed H; Armstrong, Paul; Amici, Mascia; Ligneul, Clemence; Rouse, James; El-Asrag, Mohammed E; Pantiru, Andreea; Vancollie, Valerie E; Ng, Hannah W Y; Ogbeta, Jennifer A; Goodchild, Kirstie; Ellegood, Jacob; Lelliott, Christopher J; Mullins, Jonathan G L; Bretman, Amanda; Al-Ali, Ruslan; Beetz, Christian; Al-Gazali, Lihadh; Al Shamsi, Aisha; Lerch, Jason P; Mellor, Jack R; Al Sayegh, Abeer; Ali, Manir; Inglehearn, Chris F; Clapcote, Steven J

How can we obtain truly translational mouse models to improve clinical outcomes in schizophrenia?

我们如何才能获得真正具有转化意义的小鼠模型,以改善精神分裂症的临床疗效?

Clapcote, Steven J

A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia

13q22-31染色体上的隐性遗传风险位点赋予精神分裂症易感性

Mahmood, Tariq; El-Asrag, Mohammed E; Poulter, James A; Cardno, Alastair G; Tomlinson, Anneka; Ahmed, Sophia; Al-Amri, Ahmed; Nazari, Jamshid; Neill, Joanna; Chamali, Rifka S; Kiwan, Nancy; Ghuloum, Suhaila; Alhaj, Hamid A; Randerson Moor, Juliette; Khan, Shabana; Al-Amin, Hassen; Johnson, Colin A; Woodruff, Peter; Wilkinson, Iain D; Ali, Manir; Clapcote, Steven J; Inglehearn, Chris F

Genetically altered animal models for ATP1A3-related disorders

用于研究ATP1A3相关疾病的基因改造动物模型

Ng, Hannah W Y; Ogbeta, Jennifer A; Clapcote, Steven J

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion

氯胺酮可恢复神经发育障碍相关 2p16.3 缺失小鼠模型的丘脑-前额皮质功能连接

B Hughes, Rebecca; Whittingham-Dowd, Jayde; Simmons, Rachel E; Clapcote, Steven J; Broughton, Susan J; Dawson, Neil

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

扩散张量磁共振成像和CLARITY技术在受试者自身体内的应用揭示了Nrxn2基因缺失小鼠的脑结构变化。

Pervolaraki, Eleftheria; Tyson, Adam L; Pibiri, Francesca; Poulter, Steven L; Reichelt, Amy C; Rodgers, R John; Clapcote, Steven J; Lever, Colin; Andreae, Laura C; Dachtler, James

Downregulation of the Central Noradrenergic System by Toxoplasma gondii Infection

弓形虫感染引起的中枢去甲肾上腺素能系统下调

Alsaady, Isra; Tedford, Ellen; Alsaad, Mohammad; Bristow, Greg; Kohli, Shivali; Murray, Matthew; Reeves, Matthew; Vijayabaskar, M S; Clapcote, Steven J; Wastling, Jonathan; McConkey, Glenn A