日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2

nsp14 外核糖核酸酶的酶活性对于 MERS-CoV 和 SARS-CoV-2 的复制至关重要

Natacha S Ogando, Jessika C Zevenhoven-Dobbe, Yvonne van der Meer, Peter J Bredenbeek, Clara C Posthuma #, Eric J Snijder #

Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors

复制酶跨膜亚基的适应性突变可以抵消环丝氨酸蛋白酶抑制剂对马动脉炎病毒 RNA 合成的抑制

Adriaan H de Wilde, A Linda Boomaars-van der Zanden, Anja W M de Jong, Montserrat Bárcena, Eric J Snijder #, Clara C Posthuma #

Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture

冠状病毒和动脉炎病毒在细胞培养中复制过程中对环丝氨酸蛋白酶 A 的依赖性表现出显著差异

Adriaan H de Wilde, Jessika C Zevenhoven-Dobbe, Corrine Beugeling, Udayan Chatterji, Danielle de Jong, Philippe Gallay, Karoly Szuhai, Clara C Posthuma, Eric J Snijder

Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision

醋酸铀酰诱导荧光作为纳米精度相关光电显微镜的双重对比剂

Maarten W Tuijtel, Aat A Mulder, Clara C Posthuma, Barbara van der Hoeven, Abraham J Koster, Montserrat Bárcena, Frank G A Faas, Thomas H Sharp

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

通过对 FDA 批准的化合物库进行筛选,确定了四种抑制细胞培养中中东呼吸综合征冠状病毒复制的小分子抑制剂

Adriaan H de Wilde, Dirk Jochmans, Clara C Posthuma, Jessika C Zevenhoven-Dobbe, Stefan van Nieuwkoop, Theo M Bestebroer, Bernadette G van den Hoogen, Johan Neyts, Eric J Snijder

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

一种严重急性呼吸综合征冠状病毒蛋白复合物整合了进行性 RNA 聚合酶和核酸外切酶活性

Lorenzo Subissi, Clara C Posthuma, Axelle Collet, Jessika C Zevenhoven-Dobbe, Alexander E Gorbalenya, Etienne Decroly, Eric J Snijder, Bruno Canard, Isabelle Imbert

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle

泛素-蛋白酶体系统在冠状病毒感染周期的各个阶段发挥重要作用

Matthijs Raaben, Clara C Posthuma, Monique H Verheije, Eddie G te Lintelo, Marjolein Kikkert, Jan W Drijfhout, Eric J Snijder, Peter J M Rottier, Cornelis A M de Haan