日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Profile of NT-0527, a brain penetrant NLRP3 Inflammasome inhibitor suitable as an in vivo tool compound for neuroinflammatory disorders.

NT-0527 是一种可穿透血脑屏障的 NLRP3 炎症小体抑制剂,适用于作为神经炎症性疾病的体内治疗药物

Harrison David, Billinton Andy, Bock Mark G, Clarke Nicholas P, Digby Zsofia, Gabel Christopher A, Lindsay Nicola, Reader Valérie, Scanlon Jane, Smolak Pamela, Thornton Peter, Wescott Heather, Watt Alan P

Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice

过继免疫疗法联合肿瘤内 TLR 激动剂输送可根除小鼠已形成的黑色素瘤

Sally M Amos, Hollie J Pegram, Jennifer A Westwood, Liza B John, Christel Devaud, Chris J Clarke, Nicholas P Restifo, Mark J Smyth, Phillip K Darcy, Michael H Kershaw