Clarke Oliver B相关文献与解析，生知库 | 链接生命科学的每一步

Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)

阴离子脂质对阴离子交换剂 1 (AE1) 构象转变能量景观的影响

Chen, Tianle; Vallese, Francesca; Gil-Iturbe, Eva; Kim, Kookjoo; Calì, Tito; Quick, Matthias; Clarke, Oliver B; Tajkhorshid, Emad

发表日期：2025

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Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies.

利用二价纳米抗体靶向募集 NEDD4-2 来抑制离子通道。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-67068-x

Darko-Boateng Arden, Afriyie Emmanuel, Morgenstern Travis J, Shanmugam Sri Karthika, Zou Xinle, Laloudakis Yianni D, Choudhury Papiya, Desai Meera, Kass Robert S, Vallese Francesca, Clarke Oliver B, Colecraft Henry M

NEDD4

发表日期：2025

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Promiscuous G-protein activation by the calcium-sensing receptor

钙敏感受体对G蛋白的非特异性激活

期刊:Nature

影响因子:48.5

doi:10.1038/s41586-024-07331-1

Zuo, Hao; Park, Jinseo; Frangaj, Aurel; Ye, Jianxiang; Lu, Guanqi; Manning, Jamie J; Asher, Wesley B; Lu, Zhengyuan; Hu, Guo-Bin; Wang, Liguo; Mendez, Joshua; Eng, Edward; Zhang, Zhening; Lin, Xin; Grassucci, Robert; Hendrickson, Wayne A; Clarke, Oliver B; Javitch, Jonathan A; Conigrave, Arthur D; Fan, Qing R

信号转导

发表日期：2024

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Structural and molecular basis of choline uptake into the brain by FLVCR2.

FLVCR2介导的胆碱进入大脑的结构和分子基础

期刊:Nature

影响因子:48.5

doi:10.1038/s41586-024-07326-y

Cater Rosemary J, Mukherjee Dibyanti, Gil-Iturbe Eva, Erramilli Satchal K, Chen Ting, Koo Katie, Santander NicolÃ¡s, Reckers Andrew, Kloss Brian, Gawda Tomasz, Choy Brendon C, Zhang Zhening, Katewa Aditya, Larpthaveesarp Amara, Huang Eric J, Mooney Scott W J, Clarke Oliver B, Yee Sook Wah, Giacomini Kathleen M, Kossiakoff Anthony A, Quick Matthias, Arnold Thomas, Mancia Filippo

Structural identification of the RY12 domain of RyR1 as an ADP sensor and the target of the malignant hyperthermia therapeutic dantrolene

通过结构鉴定，确定 RyR1 的 RY12 结构域为 ADP 传感器，并且是恶性高热疗法药物丹曲林的靶点。

期刊:

影响因子:

doi:10.1101/2024.10.21.619409

Kim, Kookjoo; Li, Huan; Yuan, Qi; Melville, Zephan; Zalk, Ran; des Georges, Amédée; Frank, Joachim; Hendrickson, Wayne A; Marks, Andrew R; Clarke, Oliver B

发表日期：2024

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Crystal structure of LGR ligand α2/β5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones

秀丽隐杆线虫LGR配体α2/β5的晶体结构及其对糖蛋白激素进化的意义

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2218630120

Gong, Zhen; Wang, Wei; El Omari, Kamel; Lebedev, Andrey A; Clarke, Oliver B; Hendrickson, Wayne A

Stomatin encapsulates aquaporin-1 and urea transporter-B in the erythrocyte membrane

斯托马汀将水通道蛋白-1和尿素转运蛋白-B包裹在红细胞膜上。

The vault particle is enclosed by a C13-symmetric cap with a positively charged exterior

该金库粒子被一个具有带正电荷的外部的C13对称帽所包裹

Structural dynamics and permeability of the TRPV3 pentamer

TRPV3五聚体的结构动力学和渗透性

Structure of an LGR dimer, an evolutionary predecessor of glycoprotein hormone receptors

LGR二聚体的结构，它是糖蛋白激素受体的进化前体

Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)

阴离子脂质对阴离子交换剂 1 (AE1) 构象转变能量景观的影响

Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies.

利用二价纳米抗体靶向募集 NEDD4-2 来抑制离子通道。

Promiscuous G-protein activation by the calcium-sensing receptor

钙敏感受体对G蛋白的非特异性激活

Structural and molecular basis of choline uptake into the brain by FLVCR2.

FLVCR2介导的胆碱进入大脑的结构和分子基础

Structural identification of the RY12 domain of RyR1 as an ADP sensor and the target of the malignant hyperthermia therapeutic dantrolene

通过结构鉴定，确定 RyR1 的 RY12 结构域为 ADP 传感器，并且是恶性高热疗法药物丹曲林的靶点。

Crystal structure of LGR ligand α2/β5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones

秀丽隐杆线虫LGR配体α2/β5的晶体结构及其对糖蛋白激素进化的意义