日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rational design and in vivo validation of capsid inhibitors for enterovirus D68.

肠道病毒D68衣壳抑制剂的合理设计及体内验证。

Li Kan, Rudy Michael J, Klose Thomas, Tan Haozhou, Wu Xiangmeng, Demssie Hiwot A, Anderson Jacqueline S, Jadhav Prakash, Zhang Qing-Yu, Clarke Penny, Kuhn Richard J, Tyler Kenneth L, Wang Jun

A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis.

合理设计的 2C 抑制剂可防止感染肠道病毒 D68 的小鼠出现瘫痪

Li Kan, Rudy Michael J, Hu Yanmei, Tan Haozhou, Lambrinidis George, Wu Xiangmeng, Georgiou Kyriakos, Tan Bin, Frost Joshua, Wilson Courtney, Clarke Penny, Kolocouris Antonios, Zhang Qing-Yu, Tyler Kenneth L, Wang Jun

EV68-228-N monoclonal antibody treatment halts progression of paralysis in a mouse model of EV-D68 induced acute flaccid myelitis.

EV68-228-N 单克隆抗体治疗可阻止 EV-D68 诱发的急性弛缓性脊髓炎小鼠模型中瘫痪的进展

Rudy Michael J, Wilson Courtney J, Hinckley Brendan, Baker Danielle C, Royal Joshua M, Hoke Marshall P, Brennan Miles B, Vogt Matthew R, Clarke Penny, Tyler Kenneth L

Annotating very high-resolution satellite imagery: A whale case study

高分辨率卫星图像标注:以鲸鱼为例

Cubaynes, Hannah Charlotte; Clarke, Penny Joanna; Goetz, Kimberly Thea; Aldrich, Tyler; Fretwell, Peter Thomas; Leonard, Kathleen Elise; Khan, Christin Brangwynne

Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis

在EV-D68相关急性弛缓性脊髓炎小鼠模型中,与非特异性抗体治疗的对照组相比,在瘫痪发作后给予中和抗体可减轻瘫痪的严重程度。

Rudy, Michael J; Frost, Joshua; Clarke, Penny; Tyler, Kenneth L

Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death

在西尼罗河病毒感染的离体脑片培养模型中,小胶质细胞的耗竭会导致病毒滴度升高和细胞死亡。

Stonedahl, Sarah; Leser, Jennifer Smith; Clarke, Penny; Tyler, Kenneth L

Intrinsic Innate Immune Responses Control Viral Growth and Protect against Neuronal Death in an Ex Vivo Model of West Nile Virus-Induced Central Nervous System Disease.

在西尼罗河病毒诱发的中枢神经系统疾病的离体模型中,内在的先天免疫反应控制病毒生长并防止神经元死亡

Clarke Penny, Leser J Smith, Tyler Kenneth L

The Potential of Satellite Imagery for Surveying Whales

卫星图像在鲸鱼调查中的应用潜力

Höschle, Caroline; Cubaynes, Hannah C; Clarke, Penny J; Humphries, Grant; Borowicz, Alex

The Role of Microglia during West Nile Virus Infection of the Central Nervous System

小胶质细胞在西尼罗病毒感染中枢神经系统过程中的作用

Stonedahl, Sarah; Clarke, Penny; Tyler, Kenneth L

Recruiting the innate immune system with GM-CSF to fight viral diseases, including West Nile Virus encephalitis and COVID-19

利用粒细胞-巨噬细胞集落刺激因子(GM-CSF)激活先天免疫系统,以对抗包括西尼罗河病毒性脑炎和新冠肺炎在内的病毒性疾病。

Potter, Huntington; Boyd, Timothy D; Clarke, Penny; Pelak, Victoria S; Tyler, Kenneth L