日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impaired hepatic metabolism in Hereditary Fructose Intolerance confers fructose-independent risk for steatosis and hypertriglyceridemia.

遗传性果糖不耐受症患者的肝脏代谢受损,导致与果糖无关的脂肪变性和高甘油三酯血症风险。

Fulham Melissa A, Griffin John D, Perez Sylvie, Sun Zhongyuan, Daurio Natalie A, Xing Gang, Clasquin Michelle F, Miller Melissa R, Hyde Craig L, Kelly Scott P, Boucher Magalie, Poskanzer Rachel, Gamini Ramya, Pashos Evanthia, Zhang Ying, Kuang Elaine, Fienman Josh, Bence Kendra K, Tesz Gregory J

Higher Vedolizumab Clearance Associates with Poor Therapeutic Outcomes during Intravenous Vedolizumab Maintenance Therapy in Crohn's Disease

克罗恩病患者接受静脉注射维多珠单抗维持治疗期间,较高的维多珠单抗清除率与较差的治疗效果相关。

Anjie, Suzanne I; D'Haens, Geert R; Baert, Filip; Bossuyt, Peter; Hoentjen, Frank; Clasquin, Esmé; Molnár, Tamás; Löwenberg, Mark; Vermeire, Séverine; Panetta, J Carl; Dervieux, Thierry

Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants

合成17B-HSD13底物的设计和应用揭示了保护性人类变体的催化活性得以保留

Garnsey, Michelle R; Wang, Yang; Edmonds, David J; Sammons, Matthew F; Reidich, Benjamin; Ahn, Youngwook; Ashkenazi, Yotam; Carlo, Anthony; Cerny, Matthew A; Coffman, Karen J; Culver, Jeffrey A; Dechert Schmitt, Anne-Marie; Eng, Heather; Fisher, Ethan L; Gutierrez, Jemy A; James, Larry; Jordan, Samantha; Kohrt, Jeffrey T; Kramer, Melissa; LaChapelle, Erik A; Lee, Jack C; Lee, Jisun; Li, Dongmei; Li, Zhenhong; Liu, Shenping; Liu, Jianhua; Magee, Thomas V; Miller, Melissa R; Moran, Michael; Nason, Deane M; Nedoma, Nicole L; O'Neil, Steven V; Piotrowski, Mary A; Racich, Jillian; Sommese, Ruth F; Stevens, Lucy M; Wright, Ann S; Xiao, Jun; Zhang, Liying; Zhou, Dahui; Barrandon, Ornella; Clasquin, Michelle F

Histological Outcomes and JAK-STAT Signalling in Ulcerative Colitis Patients Treated with Tofacitinib

托法替尼治疗溃疡性结肠炎患者的组织学结果和JAK-STAT信号通路

van Gennep, Sara; Fung, Ivan C N; Jong, Djuna C de; Ramkisoen, Rishand K; Clasquin, Esmé; de Jong, Jitteke; de Vries, Leonie C S; de Jonge, Wouter J; Gecse, Krisztina B; Löwenberg, Mark; Woolcott, John C; Mookhoek, Aart; D'Haens, Geert R

Murine HSD17β13 does not control liver steatosis and modestly impacts fibrosis in a sex- and diet-specific manner

小鼠 HSD17β13 不控制肝脏脂肪变性,并且以性别和饮食特异性的方式对纤维化产生轻微影响

Justin D Crane, Ornella Barrandon, Bryan Faherty, Matt Gorgoglione, Collin Crowley, Jeff Morin, Trenton T Ross, Jackson Shimkonis, Dongmei Li, Dinesh Hirenallur-Shanthappa, Magalie Boucher, Youngwook Ahn, Michelle F Clasquin

Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13

17-β-羟基类固醇脱氢酶 13 脂滴定位的结构基础

Shenping Liu, Ruth F Sommese, Nicole L Nedoma, Lucy Mae Stevens, Jason K Dutra, Liying Zhang, David J Edmonds, Yang Wang, Michelle Garnsey, Michelle F Clasquin

Mercaptopurine for the Treatment of Ulcerative Colitis: A Randomized Placebo-Controlled Trial

巯嘌呤治疗溃疡性结肠炎:一项随机安慰剂对照试验

Löwenberg, Mark; Volkers, Adriaan; van Gennep, Sara; Mookhoek, Aart; Montazeri, Nahid; Clasquin, Esmé; Duijvestein, Marjolijn; van Bodegraven, Adriaan; Rietdijk, Svend; Jansen, Jeroen; van Asseldonk, Dirk; van der Zanden, Esmerij; Dijkgraaf, Marcel; West, Rachel; de Boer, Nanne; D'Haens, Geert

'Yebo, it was a great relief': How mothers experience their children's autism diagnoses

“耶博,真是松了一口气”:母亲们如何看待孩子被诊断出患有自闭症

Manono, Mbalenhle N; Clasquin-Johnson, Mary G

BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice

BDK抑制剂可作为一种分解代谢开关,模拟禁食状态,从而改善小鼠的新陈代谢。

Eliza Bollinger ,Matthew Peloquin ,Jenna Libera ,Bina Albuquerque ,Evanthia Pashos ,Arun Shipstone ,Angela Hadjipanayis ,Zhongyuan Sun ,Gang Xing ,Michelle Clasquin ,John C Stansfield ,Brendan Tierney ,Steven Gernhardt ,C Parker Siddall ,Timothy Greizer ,Frank J Geoly ,Sarah R Vargas ,Lily C Gao ,George Williams ,Mackenzie Marshall ,Amy Rosado ,Claire Steppan ,Kevin J Filipski ,Bei B Zhang ,Russell A Miller ,Rachel J Roth Flach

Pharmacokinetic-Pharmacodynamic Model of Vedolizumab for Targeting Endoscopic Remission in Patients With Crohn Disease: Posthoc Analysis of the LOVE-CD Study

维多珠单抗靶向治疗克罗恩病患者内镜下缓解的药代动力学-药效学模型:LOVE-CD 研究的事后分析

Hanzel, Jurij; Dreesen, Erwin; Vermeire, Séverine; Löwenberg, Mark; Hoentjen, Frank; Bossuyt, Peter; Clasquin, Esmé; Baert, Filip J; D'Haens, Geert R; Mathôt, Ron