A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer
核苷酸还原酶抑制剂和组蛋白去乙酰化酶抑制剂的组合可下调 EGFR 并引发头颈癌中的 BIM 依赖性细胞凋亡
期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.430
Roland H Stauber, Shirley K Knauer, Negusse Habtemichael, Carolin Bier, Britta Unruhe, Simona Weisheit, Stephanie Spange, Frank Nonnenmacher, Verena Fetz, Torsten Ginter, Sigrid Reichardt, Claus Liebmann, Günter Schneider, Oliver H Krämer
信号转导
细胞生物学
肿瘤
表观遗传
头颈癌
其它细胞
FCM
IF
IHC-P
Apoptosis
Human
CASP3
