日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK

ETC-1002 通过 LKB1 依赖的巨噬细胞 AMPK 激活来调节免疫反应、白细胞归巢和脂肪组织炎症

Sergey Filippov, Stephen L Pinkosky, Richard J Lister, Catherine Pawloski, Jeffrey C Hanselman, Clay T Cramer, Rai Ajit K Srivastava, Timothy R Hurley, Cheryl D Bradshaw, Mark A Spahr, Roger S Newton

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism

AMP 活化蛋白激酶和 ATP-柠檬酸裂解酶是 ETC-1002 的两个不同分子靶点,ETC-1002 是一种新型脂质和碳水化合物代谢小分子调节剂

Stephen L Pinkosky, Sergey Filippov, Rai Ajit K Srivastava, Jeffrey C Hanselman, Cheryl D Bradshaw, Timothy R Hurley, Clay T Cramer, Mark A Spahr, Ashley F Brant, Jacob L Houghton, Chris Baker, Mark Naples, Khosrow Adeli, Roger S Newton