日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vitro and In Vivo Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens

口服活性碳青霉烯类抗生素替比培南(TBP)对抗生物威胁病原体的体外和体内特性研究

Clayton, Nicholas P; Jain, Akash; Halasohoris, Stephanie A; Pysz, Lisa M; Lembirik, Sanae; Zumbrun, Steven D; Kane, Christopher D; Hackett, Michael J; Pfefferle, Denise; Smiley, M Autumn; Anderson, Michael S; Heine, Henry; Meister, Gabriel T; Pucci, Michael J

An integrative systems approach identifies novel candidates in Marfan syndrome-related pathophysiology

整合系统方法识别出马凡综合征相关病理生理学中的新候选基因

Bhushan, Raghu; Altinbas, Lukas; Jäger, Marten; Zaradzki, Marcin; Lehmann, Daniel; Timmermann, Bernd; Clayton, Nicholas P; Zhu, Yunxiang; Kallenbach, Klaus; Kararigas, Georgios; Robinson, Peter N

Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche.

原纤维蛋白-1通过调节骨髓微环境中的TGFβ活性来调控骨骼干细胞分化

Smaldone Silvia, Clayton Nicholas P, del Solar Maria, Pascual Gemma, Cheng Seng H, Wentworth Bruce M, Schaffler Mitchell B, Ramirez Francesco

Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome

小鼠主动脉瘤进展过程中转化生长因子-β信号传导的二态性效应提示,联合疗法可用于治疗马凡综合征。

Cook, Jason R; Clayton, Nicholas P; Carta, Luca; Galatioto, Josephine; Chiu, Emily; Smaldone, Silvia; Nelson, Carol A; Cheng, Seng H; Wentworth, Bruce M; Ramirez, Francesco

Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease

反义寡核苷酸介导的肌肉糖原合成酶1合成抑制作为庞贝病底物减少疗法的一种方法

Clayton, Nicholas P; Nelson, Carol A; Weeden, Timothy; Taylor, Kristin M; Moreland, Rodney J; Scheule, Ronald K; Phillips, Lucy; Leger, Andrew J; Cheng, Seng H; Wentworth, Bruce M

Inhibiting TGF-β activity improves respiratory function in mdx mice.

抑制TGF-β活性可改善mdx小鼠的呼吸功能

Nelson Carol A, Hunter R Bridge, Quigley Lindsay A, Girgenrath Stefan, Weber William D, McCullough Jennifer A, Dinardo Carol J, Keefe Kelly A, Ceci Lorena, Clayton Nicholas P, McVie-Wylie Alison, Cheng Seng H, Leonard John P, Wentworth Bruce M