日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stress-induced Rab11a-exosomes induce amphiregulin-mediated cetuximab resistance in colorectal cancer

应激诱导的 Rab11a-外泌体诱导结直肠癌产生双调蛋白介导的西妥昔单抗耐药性

John D Mason, Ewan Marks, Shih-Jung Fan, Kristie McCormick, Clive Wilson, Adrian L Harris, Freddie C Hamdy, Chris Cunningham, Deborah C I Goberdhan

Accessory ESCRT-III proteins are conserved and selective regulators of Rab11a-exosome formation

辅助 ESCRT-III 蛋白是 Rab11a-外泌体形成的保守和选择性调节剂

Pauline P Marie, Shih-Jung Fan, John Mason, Adam Wells, Cláudia C Mendes, S Mark Wainwright, Sheherezade Scott, Roman Fischer, Adrian L Harris, Clive Wilson, Deborah C I Goberdhan

A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells

果蝇次级细胞中致密核心颗粒和外泌体的生物发生需要Rab6到Rab11的转变

Adam Wells, Cláudia C Mendes, Felix Castellanos, Phoebe Mountain, Tia Wright, S Mark Wainwright, M Irina Stefana, Adrian L Harris, Deborah C I Goberdhan, Clive Wilson

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

GAPDH 控制细胞外囊泡的生物合成,并增强 EV 介导的 siRNA 向大脑递送的治疗潜力

Ghulam Hassan Dar,Cláudia C Mendes,Wei-Li Kuan,Alfina A Speciale,Mariana Conceição,André Görgens,Inna Uliyakina,Miguel J Lobo,Wooi F Lim,Samir El Andaloussi,Imre Mäger,Thomas C Roberts,Roger A Barker,Deborah C I Goberdhan,Clive Wilson,Matthew J A Wood

Regulation of Dense-Core Granule Replenishment by Autocrine BMP Signalling in Drosophila Secondary Cells

果蝇次级细胞中自分泌 BMP 信号对致密核心颗粒补充的调节

Siamak Redhai, Josephine E E U Hellberg, Mark Wainwright, Sumeth W Perera, Felix Castellanos, Benjamin Kroeger, Carina Gandy, Aaron Leiblich, Laura Corrigan, Thomas Hilton, Benjamin Patel, Shih-Jung Fan, Freddie Hamdy, Deborah C I Goberdhan, Clive Wilson

BMP-regulated exosomes from Drosophila male reproductive glands reprogram female behavior

果蝇雄性生殖腺中 BMP 调节的外泌体重新编程雌性行为

Laura Corrigan, Siamak Redhai, Aaron Leiblich, Shih-Jung Fan, Sumeth M W Perera, Rachel Patel, Carina Gandy, S Mark Wainwright, John F Morris, Freddie Hamdy, Deborah C I Goberdhan, Clive Wilson

Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers

口服小分子丝裂原活化蛋白激酶激酶1/2抑制剂AZD6244(ARRY-142886)在晚期癌症患者中的I期药代动力学和药效学研究

Adjei, Alex A; Cohen, Roger B; Franklin, Wilbur; Morris, Clive; Wilson, David; Molina, Julian R; Hanson, Lorelei J; Gore, Lia; Chow, Laura; Leong, Stephen; Maloney, Lara; Gordon, Gilad; Simmons, Heidi; Marlow, Allison; Litwiler, Kevin; Brown, Suzy; Poch, Gregory; Kane, Katie; Haney, Jerry; Eckhardt, S Gail