日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stable Cas9 expression regulates cell growth by facilitating mTORC2 activation.

稳定的 Cas9 表达通过促进 mTORC2 激活来调节细胞生长。

Yu Le, Jin Yi, Chen Jianfeng, Zhu Zhichuan, Su Siyuan, Wilkerson Emily M, Gongora Joanna, Cloer Erica W, Major Michael B, Liu Pengda

Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics

肠道微生物β-葡萄糖醛酸酶影响内源性菌群稳态,并受多种治疗药物的调节。

Joshua B Simpson ,Morgan E Walker ,Joshua J Sekela ,Samantha M Ivey ,Parth B Jariwala ,Cameron M Storch ,Mark E Kowalewski ,Amanda L Graboski ,Adam D Lietzan ,William G Walton ,Kacey A Davis ,Erica W Cloer ,Valentina Borlandelli ,Yun-Chung Hsiao ,Lee R Roberts ,David H Perlman ,Xue Liang ,Hermen S Overkleeft ,Aadra P Bhatt ,Kun Lu ,Matthew R Redinbo

Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency

经过基因工程改造的Cas9变体可绕过Keap1介导的降解,从而提高人类细胞中的表观基因组编辑效率。

Jianfeng Chen ,Siyuan Su ,Adrian Pickar-Oliver ,Anna M Chiarella ,Quentin Hahn ,Dennis Goldfarb ,Erica W Cloer ,George W Small ,Smaran Sivashankar ,Dale A Ramsden ,Michael B Major ,Nathaniel A Hathaway ,Charles A Gersbach ,Pengda Liu

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity

STING 抑制线粒体 VDAC2 来调控不依赖于先天免疫的 RCC 生长

Zhichuan Zhu, Xin Zhou, Hongwei Du, Erica W Cloer, Jiaming Zhang, Liu Mei, Ying Wang, Xianming Tan, Austin J Hepperla, Jeremy M Simon, Jeanette Gowen Cook, Michael B Major, Gianpietro Dotti, Pengda Liu

Visualizing an Allosteric Intermediate Using CuAAC Stabilization of an NMR Mixed Labeled Dimer

利用 CuAAC 反应稳定 NMR 混合标记二聚体可视化变构中间体

Sapienza, Paul J; Currie, Michelle M; Lancaster, Noah M; Li, Kelin; Aubé, Jeffrey; Goldfarb, Dennis; Cloer, Erica W; Major, Michael B; Lee, Andrew L

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

TRIM9/TRIM67 神经元相互作用组揭示了形态发生的新激活因子

Shalini Menon, Dennis Goldfarb, Chris T Ho, Erica W Cloer, Nicholas P Boyer, Christopher Hardie, Andrew J Bock, Emma C Johnson, Joel Anil, M Ben Major, Stephanie L Gupton

Mesenchymal stromal cell-derived extracellular vesicles reduce lung inflammation and damage in nonclinical acute lung injury: Implications for COVID-19

间充质干细胞来源的细胞外囊泡可减轻非临床急性肺损伤中的肺部炎症和损伤:对 COVID-19 的启示

Caryn Cloer ,Laila Roudsari ,Lauren Rochelle ,Timothy Petrie ,Michaela Welch ,Joseph Charest ,Kelly Tan ,Li Fugang ,Thomas Petersen ,Roger Ilagan ,Sarah Hogan

Improving RNA Branching Predictions: Advances and Limitations

改进 RNA 分支预测:进展与局限性

Svetlana Poznanović, Carson Wood, Michael Cloer, Christine Heitsch

Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling

利用基于活性的蛋白质谱分析发现驱动药物毒性的微生物酶

Jariwala, Parth B; Pellock, Samuel J; Goldfarb, Dennis; Cloer, Erica W; Artola, Marta; Simpson, Joshua B; Bhatt, Aadra P; Walton, William G; Roberts, Lee R; Major, Michael B; Davies, Gideon J; Overkleeft, Herman S; Redinbo, Matthew R

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis

PTEN 信号和 mTORC1 介导的合成代谢的独立作用和分叉是 IL-7 驱动的 B 淋巴细胞生成的基础

Hu Zeng, Mei Yu, Haiyan Tan, Yuxin Li, Wei Su, Hao Shi, Yogesh Dhungana, Cliff Guy, Geoffrey Neale, Caryn Cloer, Junmin Peng, Demin Wang, Hongbo Chi