Cobb Melanie H相关文献与解析，生知库 | 链接生命科学的每一步

Wnt signaling inhibits casein kinase 1Î± activity by modulating its interaction with protein phosphatase 2A.

Wnt信号通过调节酪蛋白激酶1α与蛋白磷酸酶2A的相互作用来抑制酪蛋白激酶1α的活性。

doi:10.1016/j.celrep.2025.115274

Shen Chen, Lu Wenhui, Merugu Siva B, Bharti Aradhana, Afify Said M, Schnitkey Lauren, Wynn Daniel T, Yang Fan, Rohwetter Thomas M, Nayak Anmada, Bunnag Nawat, Cywiak Carolina, Tang Hsin-Yao, Harris Brent T, Albanese Christopher, Ihemelandu Chukwuemeka, Cobb Melanie H, Kettenbach Arminja, Lee Ethan, Ahmed Yashi, Robbins David J

信号转导

发表日期：2025

文献求助收藏

Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway.

激酶相互作用分析预测 WNK-OSR1/SPAK 通路的作用

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-08551-5

Taylor Clinton A 4th, Jung Ji-Ung, Gallolu Kankanamalage Sachith, Li Justin, Grzemska Magdalena, Jaykumar Ankita B, Earnest Svetlana, Stippec Steve, Saha Purbita, Sauceda Eustolia, Cobb Melanie H

信号转导

发表日期：2025

文献求助收藏

ASCL1 Restrains ERK1/2 to Promote Survival of a Subset of Neuroendocrine Lung Cancers.

ASCL1抑制ERK1/2促进部分神经内分泌肺癌的存活

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-24-0355

Martin-Vega Ana, Earnest Svetlana A, Augustyn Alexander, Wichaidit Chonlarat, Girard Luc, Peyton Michael, Minna John D, Johnson Jane E, Cobb Melanie H

SMURF1/2 Are Novel Regulators of WNK1 Stability.

SMURF1/2 是 WNK1 稳定性的新型调节因子

期刊:

影响因子:

doi:10.3390/kinasesphosphatases2030019

Jaykumar Ankita B, Plumber Sakina, Binns Derk, Wichaidit Chonlarat, Luby-Phelps Katherine, Cobb Melanie H

其它

发表日期：2024

文献求助收藏

Crank up the volume: Osmotic stress induces WNK1 phase separation

提高音量：渗透压应激诱导WNK1相分离

期刊:Cell Research

影响因子:25.9

doi:10.1038/s41422-022-00763-2

Jung, Ji-Ung; Taylor, Clinton A 4th; Cobb, Melanie H

WNK1 controls endosomal trafficking through TRIM27-dependent regulation of actin assembly

WNK1通过TRIM27依赖性调控肌动蛋白组装来控制内体运输。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2300310120

Jung, Ji-Ung; Cobb, Melanie H

Navigating the ERK1/2 MAPK Cascade

导航 ERK1/2 MAPK 级联

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom13101555

Martin-Vega, Ana; Cobb, Melanie H

MAPK/ERK

发表日期：2023

文献求助收藏

Small molecule glucagon release inhibitors with activity in human islets

对人胰岛具有活性的小分子胰高血糖素释放抑制剂

期刊:Frontiers in Endocrinology

影响因子:4.6

doi:10.3389/fendo.2023.1114799

Kalwat, Michael A; Rodrigues-Dos-Santos, Karina; Binns, Derk D; Wei, Shuguang; Zhou, Anwu; Evans, Matthew R; Posner, Bruce A; Roth, Michael G; Cobb, Melanie H

发表日期：2023

文献求助收藏

65 Gene-specific risk of syndrome-associated cancers in first-degree relatives of pancreatic cancer patients with pathogenic/likely pathogenic variants

65 携带致病性/可能致病性变异的胰腺癌患者一级亲属罹患综合征相关癌症的基因特异性风险

期刊:

影响因子:

doi:10.1101/2023.06.15.545148

Martin-Vega, Ana; Earnest, Svetlana; Augustyn, Alexander; Wichaidit, Chonlarat; Gazdar, Adi; Girard, Luc; Peyton, Michael; Kollipara, Rahul K; Minna, John D; Johnson, Jane E; Cobb, Melanie H; Chen, Xuan; Rabe, Kari G; Meyer, Margaret A; Kemppainen, Jennifer L; Horibe, Masayasu; Chandra, Shruti; Majumder, Shounak; Petersen, Gloria M

Activation of WNK1 signaling through Piezo1.

通过 Piezo1 激活 WNK1 信号通路

Wnt signaling inhibits casein kinase 1Î± activity by modulating its interaction with protein phosphatase 2A.

Wnt信号通过调节酪蛋白激酶1α与蛋白磷酸酶2A的相互作用来抑制酪蛋白激酶1α的活性。

Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway.

激酶相互作用分析预测 WNK-OSR1/SPAK 通路的作用

ASCL1 Restrains ERK1/2 to Promote Survival of a Subset of Neuroendocrine Lung Cancers.

ASCL1抑制ERK1/2促进部分神经内分泌肺癌的存活

SMURF1/2 Are Novel Regulators of WNK1 Stability.

SMURF1/2 是 WNK1 稳定性的新型调节因子

Crank up the volume: Osmotic stress induces WNK1 phase separation

提高音量：渗透压应激诱导WNK1相分离

WNK1 controls endosomal trafficking through TRIM27-dependent regulation of actin assembly

WNK1通过TRIM27依赖性调控肌动蛋白组装来控制内体运输。

Navigating the ERK1/2 MAPK Cascade

导航 ERK1/2 MAPK 级联

Small molecule glucagon release inhibitors with activity in human islets

对人胰岛具有活性的小分子胰高血糖素释放抑制剂

65 Gene-specific risk of syndrome-associated cancers in first-degree relatives of pancreatic cancer patients with pathogenic/likely pathogenic variants

65 携带致病性/可能致病性变异的胰腺癌患者一级亲属罹患综合征相关癌症的基因特异性风险