日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

GID/CTLH E3 ligase complex control cell fate programs for sexual development of Plasmodium falciparum

GID/CTLH E3连接酶复合物控制恶性疟原虫有性发育的细胞命运程序

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69183-9
Marapana, Danushka S; Lopaticki, Sash; Balan, Balu; Reaksudsan, Kitsanapong; Cobbold, Simon A; Geoghegan, Niall D; Khurana, Sachin; Scally, Stephen W; Hickey, Peter; Jayakrishnan, Niva; Vaibhav, Vineet; Spall, Sukhdeep; Yousef, Jumana M; Dagley, Laura F; Goodman, Christopher D; Cozijnsen, Anton; McFadden, Geoffrey I; Rogers, Kelly L; Jex, Aaron; Komander, David; McCarthy, James S; Tonkin, Christopher J; Dixon, Matthew W A; Cowman, Alan F
细胞生物学
发育与干细胞
发表日期：2026
文献求助 收藏

Major histocompatibility class II in murine antigen presenting cells is modified with a branched K63 and K11-linked ubiquitin chain

小鼠抗原呈递细胞中的主要组织相容性复合体II类分子被分支的K63和K11连接的泛素链修饰。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-25817-4
Liu, Haiyin; Francis, Lauren; Dagley, Laura F; Cobbold, Simon A; Webb, Andrew I; Komander, David; Villadangos, Jose A; Mintern, Justine D
细胞生物学
发表日期：2025
文献求助 收藏

Functional characterisation of components in two Plasmodium falciparum Cullin-RING-Ligase complexes.

对两种恶性疟原虫 Cullin-RING-连接酶复合物的组分进行功能表征

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-05342-0
Marapana Danushka, Cobbold Simon A, Pasternak Michal, Shami Gerald J, Ralph Stuart A, Lopaticki Sash, Yousef Jumana, Vaibhav Vineet, Dagley Laura F, Komander David, Cowman Alan F
其它
发表日期：2025
文献求助 收藏

Differentiation of Toxoplasma into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase

弓形虫分化为潜伏型与中心碳代谢有关，并且需要GID/CTLH型E3泛素连接酶。

期刊:
影响因子:
doi:10.1101/2025.07.27.667068
Uboldi, Alessandro D; Khurana, Sachin; Jaywickrama, Amalie A; Lekkala-Lethakula, Sai Prasanna; Simonpietri, Amber; Singh, Karan; Hofferek, Vinzenz; Ruparel, Ushma; Whitehead, Lachlan L; Rogers, Kelly L; Garnham, Alexandra L; Scott, Nichollas; Katris, Nicholas J; McConville, Malcolm J; Komander, David; Cobbold, Simon A; Tonkin, Christopher J
代谢
发表日期：2025
文献求助 收藏

The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes

重症疟原虫的转录组分析揭示了参与重要过程的基因表达发生改变，其中包括编码表面抗原的var基因。

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.2004328
Tonkin-Hill, Gerry Q; Trianty, Leily; Noviyanti, Rintis; Nguyen, Hanh H T; Sebayang, Boni F; Lampah, Daniel A; Marfurt, Jutta; Cobbold, Simon A; Rambhatla, Janavi S; McConville, Malcolm J; Rogerson, Stephen J; Brown, Graham V; Day, Karen P; Price, Ric N; Anstey, Nicholas M; Papenfuss, Anthony T; Duffy, Michael F
发表日期：2018
文献求助 收藏

The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens

疟原虫乳酸转运蛋白PfFNT是全细胞表型筛选中发现的抗疟化合物的作用靶点

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1006180
Hapuarachchi, Sanduni V; Cobbold, Simon A; Shafik, Sarah H; Dennis, Adelaide S M; McConville, Malcolm J; Martin, Rowena E; Kirk, Kiaran; Lehane, Adele M
细胞生物学
发表日期：2017
文献求助 收藏

Metabolomics-Based Screening of the Malaria Box Reveals both Novel and Established Mechanisms of Action

基于代谢组学的疟疾靶标筛选揭示了新的和已知的药理机制

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01226-16
Creek, Darren J; Chua, Hwa H; Cobbold, Simon A; Nijagal, Brunda; MacRae, James I; Dickerman, Benjamin K; Gilson, Paul R; Ralph, Stuart A; McConville, Malcolm J
微生物学
疟疾
代谢
发表日期：2016
文献求助 收藏

Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite

蛋白质组范围分析揭示疟原虫主要蛋白质复合物中广泛的赖氨酸乙酰化

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep19722
Cobbold, Simon A; Santos, Joana M; Ochoa, Alejandro; Perlman, David H; Llinás, Manuel
乙酰化
表观遗传
发表日期：2016
文献求助 收藏

Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

鉴定能够双重靶向恶性疟原虫血液期新通透性途径和二氢乳清酸脱氢酶的抑制剂

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep37502
Dickerman, Benjamin K; Elsworth, Brendan; Cobbold, Simon A; Nie, Catherine Q; McConville, Malcolm J; Crabb, Brendan S; Gilson, Paul R
发表日期：2016
文献求助 收藏

Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum

靶向人类疟原虫恶性疟原虫的NAD+代谢

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0094061
O'Hara, Jessica K; Kerwin, Lewis J; Cobbold, Simon A; Tai, Jonathan; Bedell, Thomas A; Reider, Paul J; Llinás, Manuel
代谢
发表日期：2014
文献求助 收藏