日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Self-amplifying NRF2-EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer.

自我扩增的 NRF2-EZH2 表观遗传环将 KRAS 启动的祖细胞转化为侵袭性胰腺癌

Antonucci Laura, Li Na, Duran Angeles, Cobo Isidoro, Nicoletti Chiara, Watari Kosuke, Nandi Shuvro Prokash, Zhu Feng, Zhao Yongmei, Riahi Irene, Tsuda Motoyuki, Shah Vidhi M, Morgan Terry, Waugh Trent, Caputo Luca, Liu Yuan, Rundberg Nilsson Alexandra, Xian Hongxu, Todoric Jelena, Gu Li, Sanchez-Lopez Elsa, Eibl Guido, Vucic Emily A, Krawczyk Michal, Xu Qianlan, Lowy Andrew M, Hatzivassiliou Georgia, Roose-Girma Merone, Skowronska-Krawczyk Dorota, Scott David A, Bar-Sagi Dafna, Tamayo Pablo, Wu Ying, Sears Rosalie C, Glass Christopher K, Alexandrov Ludmil B, Puri Pier Lorenzo, Dawson David W, Hu Yinling, Diaz-Meco Maria T, Moscat Jorge, Karin Michael

Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.

巨噬细胞对颗粒的摄取会触发分叉的转录通路,从而差异性地调节炎症和溶酶体基因表达

Cobo Isidoro, Murillo-Saich Jessica, Alishala Mohnish, Calderon Stephen, Coras Roxana, Hemming Benjamin, Inkum Faith, Rosas Fiorella, Takei Riku, Spann Nathan, Prohaska Thomas A, Alabarse Paulo V G, Jeong Se-Jin, Nickl Christian K, Cheng Anyan, Li Benjamin, Vogel Andrea, Weichhart Thomas, Fuster José J, Le Thomas, Bradstreet Tara R, Webber Ashlee M, Edelson Brian T, Razani Babak, Ebert Benjamin L, Taneja Reshma, Terkeltaub Robert, Bryan Ru Liu, Guma Monica, Glass Christopher K

Hepatic Inactivation of Carnitine Palmitoyltransferase 1a Lowers ApoB-Containing Lipoproteins in Mice

肝脏中肉碱棕榈酰转移酶1a的失活会降低小鼠体内含载脂蛋白B的脂蛋白水平

Helsley, Robert N; Zelows, Mikala M; Noffsinger, Victoria P; Anspach, Garrett B; Dharanipragada, Nikitha; Mead, Anna E; Cobo, Isidoro; Carter, Abigail; Wu, Qinglin; Shalaurova, Irina; Saito, Kai; Morganti, Josh M; Gordon, Scott M; Graf, Gregory A

Chromatin structural gene expression stratifies cardiac cell populations in health and disease

染色质结构基因表达在健康和疾病状态下对心肌细胞群进行分层。

Geng, Xiaoxiao; Pradeep, Rujula; Porter, Riley; García-Gutiérrez, Lucia; Xie, Min; Wende, Adam R; Zhang, Jianyi; Cobo, Isidoro; Nguyen, Thanh; Rosa-Garrido, Manuel

Epigenetic Regulation of Nutrient Transporters in Rheumatoid Arthritis Fibroblast-like Synoviocytes

类风湿性关节炎成纤维细胞样滑膜细胞中营养转运蛋白的表观遗传调控

Torres, Alyssa; Pedersen, Brian; Cobo, Isidoro; Ai, Rizi; Coras, Roxana; Murillo-Saich, Jessica; Nygaard, Gyrid; Sanchez-Lopez, Elsa; Murphy, Anne; Wang, Wei; Firestein, Gary S; Guma, Monica

The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development

早期发育过程中组织扩散期间径向插入的分子基础

Szabó, András; Cobo, Isidoro; Omara, Sharif; McLachlan, Sophie; Keller, Ray; Mayor, Roberto