日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Envelope-dimer epitope 1 (EDE1) antibody (C10) treatment significantly reduces Zika virus replication in the male and female reproductive tracts

包膜二聚体表位1(EDE1)抗体(C10)治疗可显著降低寨卡病毒在男性和女性生殖道中的复制。

Schramm, Nathaniel J; Kovarova, Martina; Manzoor, Shajer; Cockrell, Adam S; Spagnuolo, Rae Ann; Amblard, Franck; Bassit, Leda; Schinazi, Raymond F; Baric, Ralph S; Wahl, Angela; Garcia, J Victor

Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity

肺上皮细胞稳态和免疫失调是导致中东呼吸综合征冠状病毒疾病严重程度增加的原因之一。

Sims, Amy C; Schäfer, Alexandra; Okuda, Kenichi; Leist, Sarah R; Kocher, Jacob F; Cockrell, Adam S; Hawkins, Padraig E; Furusho, Minako; Jensen, Kara L; Kyle, Jennifer E; Burnum-Johnson, Kristin E; Stratton, Kelly G; Lamar, Natalie C; Niccora, Carrie D; Weitz, Karl K; Smith, Richard D; Metz, Thomas O; Waters, Katrina M; Boucher, Richard C; Montgomery, Stephanie A; Baric, Ralph S; Sheahan, Timothy P

The pan-variant potential of light: 425 nm light inactivates SARS-CoV-2 variants of concern and non-cytotoxic doses reduce viral titers in human airway epithelial cells.

光的泛变异潜力:425 纳米光可使受关注的 SARS-CoV-2 变异株失活,且非细胞毒性剂量可降低人类呼吸道上皮细胞中的病毒滴度

Stasko Nathan, Arwood Leslee, Jandick Nicole, Spragion Derry, Roberts Rachel C, Setién Mónica, Henson Ibrahim, Annas Abigail, Fulcher M Leslie, Brotton Marisa, Kummer Larry, Szaba Frank, Reagan Matt, Lanzer Kathleen, Cookenham Tres, Casey Sean, Kothapalli Nagarama, Hart Tricia, Bradrick Shelton S, Emerson David, Cockrell Adam S, Randell Scott H, Kocher Jacob F

Delivery of a Muscle-Targeted Adeno-Associated Vector Via Ex Vivo Normothermic Perfusion Is Efficient, Durable, and Safe in a Preclinical Porcine Heart Transplant Model

在临床前猪心脏移植模型中,通过体外常温灌注递送肌肉靶向腺相关载体是高效、持久且安全的。

Dewan, Krish C; Chen, Jeng-Wei; Lobo, Alejandro A; Gross, Ryan T; Wang, Chunbo; Rivera, Karla G; Tran, Keely Dieplin; Ngeve, Smith; Johnston, Violet G; Wendell, David; Glass, Carolyn K; Evans, Amy; Ho, Sam; Lezberg, Paul; Casy, Widler; Bazile, Marla; Patel, Kruti; Cockrell, Adam S; Milano, Carmelo A; Bowles, Dawn

A randomized, controlled, feasibility study of RD-X19 in subjects with mild-to-moderate COVID-19 in the outpatient setting

一项针对门诊轻度至中度 COVID-19 患者的 RD-X19 随机对照可行性研究

Stasko, Nathan; Cockrell, Adam S; Kocher, Jacob F; Henson, Ibrahim; Emerson, David; Wang, Ye; Smith, Jonathan R; Henderson, Nathan H; Wood, Hillary; Bradrick, Shelton S; Jones, Terry; Santander, Jorge; McNeil, John G

Visible blue light inhibits infection and replication of SARS-CoV-2 at doses that are well-tolerated by human respiratory tissue

可见蓝光在人体呼吸组织可耐受的剂量下,能够抑制SARS-CoV-2的感染和复制。

Stasko, Nathan; Kocher, Jacob F; Annas, Abigail; Henson, Ibrahim; Seitz, Theresa S; Miller, Joy M; Arwood, Leslee; Roberts, Rachel C; Womble, Thomas M; Keller, Emily G; Emerson, Soren; Bergmann, Michael; Sheesley, Ashley N Y; Strong, Rebecca J; Hurst, Brett L; Emerson, David; Tarbet, E Bart; Bradrick, Shelton S; Cockrell, Adam S

Hypergraph models of biological networks to identify genes critical to pathogenic viral response

利用生物网络超图模型识别对致病病毒反应至关重要的基因

Feng, Song; Heath, Emily; Jefferson, Brett; Joslyn, Cliff; Kvinge, Henry; Mitchell, Hugh D; Praggastis, Brenda; Eisfeld, Amie J; Sims, Amy C; Thackray, Larissa B; Fan, Shufang; Walters, Kevin B; Halfmann, Peter J; Westhoff-Smith, Danielle; Tan, Qing; Menachery, Vineet D; Sheahan, Timothy P; Cockrell, Adam S; Kocher, Jacob F; Stratton, Kelly G; Heller, Natalie C; Bramer, Lisa M; Diamond, Michael S; Baric, Ralph S; Waters, Katrina M; Kawaoka, Yoshihiro; McDermott, Jason E; Purvine, Emilie

Genetically Engineering a Susceptible Mouse Model for MERS-CoV-Induced Acute Respiratory Distress Syndrome

利用基因工程技术构建易感小鼠模型,用于研究中东呼吸综合征冠状病毒(MERS-CoV)诱发的急性呼吸窘迫综合征

Leist, Sarah R; Cockrell, Adam S

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis

人类钠碘同向转运蛋白作为报告基因用于研究中东呼吸综合征冠状病毒的发病机制

Chefer, Svetlana; Seidel, Jurgen; Cockrell, Adam S; Yount, Boyd; Solomon, Jeffrey; Hagen, Katie R; Liu, David X; Huzella, Louis M; Kumar, Mia R; Postnikova, Elena; Bohannon, J Kyle; Lackemeyer, Matthew G; Cooper, Kurt; Endlich-Frazier, Ariel; Sharma, Heema; Thomasson, David; Bartos, Christopher; Sayre, Philip J; Sims, Amy; Dyall, Julie; Holbrook, Michael R; Jahrling, Peter B; Baric, Ralph S; Johnson, Reed F

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice

在小鼠中模拟新发和新发人类冠状病毒的致病机制

Cockrell, Adam S; Leist, Sarah R; Douglas, Madeline G; Baric, Ralph S