日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic Targeting of Microglial Hexokinase-2 Recalibrates Inflammasome Activation and Improves Functional Recovery After Traumatic Brain Injury

靶向小胶质细胞己糖激酶-2的治疗可重新调节炎症小体激活并改善创伤性脑损伤后的功能恢复

Mera-Reina, Claudia; Codocedo, Juan F; Fallen, Paul B; Scott, Jack; Lasagna-Reeves, Cristian A; Landreth, Gary E

Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer's progression

免疫代谢治疗靶向揭示了己糖激酶 2 剂量对小胶质细胞活化和阿尔茨海默病进展的关键依赖

Juan F Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Paul B Fallen, Shweta S Puntambekar, Brad T Casali, Nur Jury-Garfe, Pablo Martinez, Cristian A Lasagna-Reeves, Gary E Landreth

Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis

MR1/MAIT细胞轴对阿尔茨海默病病理时间发展的调控

Season K Wyatt-Johnson ,Holly N Kersey ,Juan F Codocedo ,Kathy L Newell ,Gary E Landreth ,Bruce T Lamb ,Adrian L Oblak ,Randy R Brutkiewicz

Therapeutic targeting of immunometabolism in Alzheimer's disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression

阿尔茨海默病免疫代谢的治疗靶向性揭示了己糖激酶 2 剂量对小胶质细胞活化和疾病进展的关键依赖性

Juan F Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Shweta S Puntambekar, Brad T Casali, Nur Jury, Pablo Martinez, Cristian A Lasagna-Reeves, Gary E Landreth

Bassoon contributes to tau-seed propagation and neurotoxicity

巴松管促进 tau 种子传播和神经毒性

Pablo Martinez ,Henika Patel ,Yanwen You ,Nur Jury ,Abigail Perkins ,Audrey Lee-Gosselin ,Xavier Taylor ,Yingjian You ,Gonzalo Viana Di Prisco ,Xiaoqing Huang ,Sayan Dutta ,Aruna B Wijeratne ,Javier Redding-Ochoa ,Syed Salman Shahid ,Juan F Codocedo ,Sehong Min ,Gary E Landreth ,Amber L Mosley ,Yu-Chien Wu ,David L McKinzie ,Jean-Christophe Rochet ,Jie Zhang ,Brady K Atwood ,Juan Troncoso ,Cristian A Lasagna-Reeves

The intersection of metabolism and inflammation is governed by the intracellular topology of hexokinases and the metabolic fate of glucose

代谢与炎症的相互作用受己糖激酶的细胞内拓扑结构和葡萄糖的代谢命运调控。

Codocedo, Juan F; Landreth, Gary E

Effects of long-lasting social isolation and re-socialization on cognitive performance and brain activity: a longitudinal study in Octodon degus

长期社会隔离和重新社会化对认知表现和大脑活动的影响:对八齿鼠的纵向研究

Daniela S Rivera, Carolina B Lindsay, Carolina A Oliva, Juan Francisco Codocedo, Francisco Bozinovic, Nibaldo C Inestrosa

TREM2 is required for microglial instruction of astrocytic synaptic engulfment in neurodevelopment

TREM2 是神经发育过程中小胶质细胞指导星形胶质细胞突触吞噬所必需的

Taylor R Jay, Victoria E von Saucken, Braulio Muñoz, Juan F Codocedo, Brady K Atwood, Bruce T Lamb, Gary E Landreth

Wnt-related SynGAP1 is a neuroprotective factor of glutamatergic synapses against Aβ oligomers

Wnt相关蛋白SynGAP1是谷氨酸能突触对抗Aβ寡聚体的神经保护因子。

Codocedo, Juan F; Montecinos-Oliva, Carla; Inestrosa, Nibaldo C